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Safety and Preliminary Efficacy of Mesenchymal Stromal Cell (ORBCEL-M) Therapy in Diabetic Kidney Disease: A Randomized Clinical Trial (NEPHSTROM).
Perico N, Remuzzi G, Griffin MD, Cockwell P, Maxwell AP, Casiraghi F, Rubis N, Peracchi T, Villa A, Todeschini M, Carrara F, Magee BA, Ruggenenti PL, Rota S, Cappelletti L, McInerney V, Griffin TP, Islam MN, Introna M, Pedrini O, Golay J, Finnerty AA, Smythe J, Fibbe WE, Elliman SJ, O'Brien T; NEPHSTROM Trial Consortium. Perico N, et al. Among authors: finnerty aa. J Am Soc Nephrol. 2023 Oct 1;34(10):1733-1751. doi: 10.1681/ASN.0000000000000189. Epub 2023 Aug 10. J Am Soc Nephrol. 2023. PMID: 37560967 Clinical Trial.
Marrow changes and reduced proliferative capacity of mesenchymal stromal cells from patients with "no-option" critical limb ischemia; observations on feasibility of the autologous approach from a clinical trial.
Mohamed SA, Duffy A, McInerney V, Krawczyk J, Hayat A, Naughton S, Finnerty A, Holohan M, Liew A, Tubassam M, Walsh SR, O'Brien T, Howard L. Mohamed SA, et al. Cytotherapy. 2022 Dec;24(12):1259-1267. doi: 10.1016/j.jcyt.2022.07.002. Epub 2022 Aug 20. Cytotherapy. 2022. PMID: 35999133 Free article.
Autologous bone marrow mesenchymal stromal cell therapy for "no-option" critical limb ischemia is limited by karyotype abnormalities.
Mohamed SA, Howard L, McInerney V, Hayat A, Krawczyk J, Naughton S, Finnerty A, Holohan M, Duffy A, Moloney T, Kavanagh E, Burke P, Liew A, Tubassam M, Walsh SR, O'Brien T. Mohamed SA, et al. Cytotherapy. 2020 Jun;22(6):313-321. doi: 10.1016/j.jcyt.2020.02.007. Epub 2020 Apr 6. Cytotherapy. 2020. PMID: 32273232 Free article. Clinical Trial.
GMP-Compliant Production of Autologous Adipose-Derived Stromal Cells in the NANT 001 Closed Automated Bioreactor.
Fitzgerald JC, Duffy N, Cattaruzzi G, Vitrani F, Paulitti A, Mazzarol F, Mauro P, Sfiligoj A, Curcio F, Jones DM, McInerney V, Krawczyk J, Kelly J, Finnerty A, McDonagh K, McCabe U, Duggan M, Connolly L, Shaw G, Murphy M, Barry F. Fitzgerald JC, et al. Front Bioeng Biotechnol. 2022 Mar 9;10:834267. doi: 10.3389/fbioe.2022.834267. eCollection 2022. Front Bioeng Biotechnol. 2022. PMID: 35356775 Free PMC article.