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Comparative Clustering (CompaCt) of eukaryote complexomes identifies novel interactions and sheds light on protein complex evolution.
van Strien J, Evers F, Lutikurti M, Berendsen SL, Garanto A, van Gemert GJ, Cabrera-Orefice A, Rodenburg RJ, Brandt U, Kooij TWA, Huynen MA. van Strien J, et al. Among authors: van gemert gj. PLoS Comput Biol. 2023 Aug 7;19(8):e1011090. doi: 10.1371/journal.pcbi.1011090. eCollection 2023 Aug. PLoS Comput Biol. 2023. PMID: 37549177 Free PMC article.
Detailing organelle division and segregation in Plasmodium falciparum.
Verhoef JMJ, Boshoven C, Evers F, Akkerman LJ, Gijsbrechts BCA, van de Vegte-Bolmer M, van Gemert GJ, Vaidya AB, Kooij TWA. Verhoef JMJ, et al. Among authors: van gemert gj. bioRxiv [Preprint]. 2024 May 13:2024.01.30.577899. doi: 10.1101/2024.01.30.577899. bioRxiv. 2024. PMID: 38352445 Free PMC article. Preprint.
Pfs230 Domain 7 is targeted by a potent malaria transmission-blocking monoclonal antibody.
Inklaar MR, de Jong RM, Bekkering ET, Nagaoka H, Fennemann FL, Teelen K, van de Vegte-Bolmer M, van Gemert GJ, Stoter R, King CR, Proellochs NI, Bousema T, Takashima E, Tsuboi T, Jore MM. Inklaar MR, et al. Among authors: van gemert gj. NPJ Vaccines. 2023 Dec 12;8(1):186. doi: 10.1038/s41541-023-00784-x. NPJ Vaccines. 2023. PMID: 38086855 Free PMC article.
A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial.
Alkema M, Smit MJ, Marin-Mogollon C, Totté K, Teelen K, van Gemert GJ, van de Vegte-Bolmer M, Mordmüller BG, Reimer JM, Lövgren-Bengtsson KL, Sauerwein RW, Bousema T, Plieskatt J, Theisen M, Jore MM, McCall MBB. Alkema M, et al. Among authors: van gemert gj. BMC Med. 2024 Apr 23;22(1):170. doi: 10.1186/s12916-024-03379-y. BMC Med. 2024. PMID: 38649867 Free PMC article. Clinical Trial.
Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes.
Andolina C, Graumans W, Guelbeogo M, van Gemert GJ, Ramijth J, Harouna S, Soumanaba Z, Stoter R, Vegte-Bolmer M, Pangos M, Sinnis P, Collins K, Staedke SG, Tiono AB, Drakeley C, Lanke K, Bousema T. Andolina C, et al. Among authors: van gemert gj. Elife. 2024 Mar 22;12:RP90989. doi: 10.7554/eLife.90989. Elife. 2024. PMID: 38517746 Free PMC article.
Development of Plasmodium falciparum liver-stages in hepatocytes derived from human fetal liver organoid cultures.
Yang ASP, Dutta D, Kretzschmar K, Hendriks D, Puschhof J, Hu H, Boonekamp KE, van Waardenburg Y, Chuva de Sousa Lopes SM, van Gemert GJ, de Wilt JHW, Bousema T, Clevers H, Sauerwein RW. Yang ASP, et al. Among authors: van gemert gj. Nat Commun. 2023 Aug 2;14(1):4631. doi: 10.1038/s41467-023-40298-7. Nat Commun. 2023. PMID: 37532704 Free PMC article.
Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230.
Ivanochko D, Fabra-García A, Teelen K, van de Vegte-Bolmer M, van Gemert GJ, Newton J, Semesi A, de Bruijni M, Bolscher J, Ramjith J, Szabat M, Vogt S, Kraft L, Duncan S, Lee SM, Kamya MR, Feeney ME, Jagannathan P, Greenhouse B, Sauerwein RW, Richter King C, MacGill RS, Bousema T, Jore MM, Julien JP. Ivanochko D, et al. Among authors: van gemert gj. Immunity. 2023 Feb 14;56(2):420-432.e7. doi: 10.1016/j.immuni.2023.01.013. Immunity. 2023. PMID: 36792575 Free PMC article.
Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes.
Fabra-García A, Hailemariam S, de Jong RM, Janssen K, Teelen K, van de Vegte-Bolmer M, van Gemert GJ, Ivanochko D, Semesi A, McLeod B, Vos MW, de Bruijni MHC, Bolscher JM, Szabat M, Vogt S, Kraft L, Duncan S, Kamya MR, Feeney ME, Jagannathan P, Greenhouse B, Dechering KJ, Sauerwein RW, King CR, MacGill RS, Bousema T, Julien JP, Jore MM. Fabra-García A, et al. Among authors: van gemert gj. Immunity. 2023 Feb 14;56(2):406-419.e7. doi: 10.1016/j.immuni.2023.01.009. Immunity. 2023. PMID: 36792574 Free PMC article.
130 results