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Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory.
Moulder R, Välikangas T, Hirvonen MK, Suomi T, Brorsson CA, Lietzén N, Bruggraber SFA, Overbergh L, Dunger DB, Peakman M, Chmura PJ, Brunak S, Schulte AM, Mathieu C, Knip M, Elo LL, Lahesmaa R; INNODIA consortium. Moulder R, et al. Among authors: lietzen n. Diabetologia. 2023 Nov;66(11):1983-1996. doi: 10.1007/s00125-023-05974-9. Epub 2023 Aug 4. Diabetologia. 2023. PMID: 37537394 Free PMC article.
Umbilical cord blood DNA methylation in children who later develop type 1 diabetes.
Laajala E, Kalim UU, Grönroos T, Rasool O, Halla-Aho V, Konki M, Kattelus R, Mykkänen J, Nurmio M, Vähä-Mäkilä M, Kallionpää H, Lietzén N, Ghimire BR, Laiho A, Hyöty H, Elo LL, Ilonen J, Knip M, Lund RJ, Orešič M, Veijola R, Lähdesmäki H, Toppari J, Lahesmaa R. Laajala E, et al. Among authors: lietzen n. Diabetologia. 2022 Sep;65(9):1534-1540. doi: 10.1007/s00125-022-05726-1. Epub 2022 Jun 18. Diabetologia. 2022. PMID: 35716175 Free PMC article.
Serum APOC1 levels are decreased in young autoantibody positive children who rapidly progress to type 1 diabetes.
Hirvonen MK, Lietzén N, Moulder R, Bhosale SD, Koskenniemi J, Vähä-Mäkilä M, Nurmio M, Orešič M, Ilonen J, Toppari J, Veijola R, Hyöty H, Lähdesmäki H, Knip M, Cheng L, Lahesmaa R. Hirvonen MK, et al. Among authors: lietzen n. Sci Rep. 2023 Sep 24;13(1):15941. doi: 10.1038/s41598-023-43039-4. Sci Rep. 2023. PMID: 37743383 Free PMC article.
Pancreas Whole Tissue Transcriptomics Highlights the Role of the Exocrine Pancreas in Patients With Recently Diagnosed Type 1 Diabetes.
Välikangas T, Lietzén N, Jaakkola MK, Krogvold L, Eike MC, Kallionpää H, Tuomela S, Mathews C, Gerling IC, Oikarinen S, Hyöty H, Dahl-Jorgensen K, Elo LL, Lahesmaa R. Välikangas T, et al. Among authors: lietzen n. Front Endocrinol (Lausanne). 2022 Apr 13;13:861985. doi: 10.3389/fendo.2022.861985. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35498413 Free PMC article.
Permutation-based significance analysis reduces the type 1 error rate in bisulphite sequencing data analysis of human umbilical cord blood samples.
Laajala E, Halla-Aho V, Grönroos T, Kalim UU, Vähä-Mäkilä M, Nurmio M, Kallionpää H, Lietzén N, Mykkänen J, Rasool O, Toppari J, Orešič M, Knip M, Lund R, Lahesmaa R, Lähdesmäki H. Laajala E, et al. Among authors: lietzen n. Epigenetics. 2022 Dec;17(12):1608-1627. doi: 10.1080/15592294.2022.2044127. Epub 2022 Mar 4. Epigenetics. 2022. PMID: 35246015 Free PMC article.
Fast tensorial JADE.
Virta J, Lietzén N, Ilmonen P, Nordhausen K. Virta J, et al. Among authors: lietzen n. Scand Stat Theory Appl. 2021 Mar;48(1):164-187. doi: 10.1111/sjos.12445. Epub 2020 Feb 11. Scand Stat Theory Appl. 2021. PMID: 33664538 Free PMC article.
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