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Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives.
Pelliccia S, Amato J, Capasso D, Di Gaetano S, Massarotti A, Piccolo M, Irace C, Tron GC, Pagano B, Randazzo A, Novellino E, Giustiniano M. Pelliccia S, et al. Among authors: amato j. J Med Chem. 2020 Mar 12;63(5):2035-2050. doi: 10.1021/acs.jmedchem.9b00262. Epub 2019 Jul 10. J Med Chem. 2020. PMID: 31241946
Targeting the KRAS oncogene: Synthesis, physicochemical and biological evaluation of novel G-Quadruplex DNA binders.
D'Aria F, D'Amore VM, Di Leva FS, Amato J, Caterino M, Russomanno P, Salerno S, Barresi E, De Leo M, Marini AM, Taliani S, Da Settimo F, Salgado GF, Pompili L, Zizza P, Shirasawa S, Novellino E, Biroccio A, Marinelli L, Giancola C. D'Aria F, et al. Among authors: amato j. Eur J Pharm Sci. 2020 Apr 18;149:105337. doi: 10.1016/j.ejps.2020.105337. Online ahead of print. Eur J Pharm Sci. 2020. PMID: 32311457
Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand.
Tomassi S, D'Amore VM, Di Leva FS, Vannini A, Quilici G, Weinmüller M, Reichart F, Amato J, Romano B, Izzo AA, Di Maro S, Novellino E, Musco G, Gianni T, Kessler H, Marinelli L. Tomassi S, et al. Among authors: amato j. J Med Chem. 2021 May 27;64(10):6972-6984. doi: 10.1021/acs.jmedchem.1c00533. Epub 2021 May 7. J Med Chem. 2021. PMID: 33961417 Free PMC article.
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors.
Russomanno P, Assoni G, Amato J, D'Amore VM, Scaglia R, Brancaccio D, Pedrini M, Polcaro G, La Pietra V, Orlando P, Falzoni M, Cerofolini L, Giuntini S, Fragai M, Pagano B, Donati G, Novellino E, Quintavalle C, Condorelli G, Sabbatino F, Seneci P, Arosio D, Pepe S, Marinelli L. Russomanno P, et al. Among authors: amato j. J Med Chem. 2021 Nov 11;64(21):16020-16045. doi: 10.1021/acs.jmedchem.1c01409. Epub 2021 Oct 20. J Med Chem. 2021. PMID: 34670084
282 results