Perry MD - Search Results

1

Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia.

Thorpe J, Perry MD, Contreras O, Hurley E, Parker G, Harvey RP, Hill AP, Vandenberg JI. Thorpe J, et al. Among authors: perry md. Stem Cell Res Ther. 2023 Jul 27;14(1):183. doi: 10.1186/s13287-023-03405-5. Stem Cell Res Ther. 2023. PMID: 37501071 Free PMC article.

2

A Universal and Robust Integrated Platform for the Scalable Production of Human Cardiomyocytes From Pluripotent Stem Cells.

Fonoudi H, Ansari H, Abbasalizadeh S, Larijani MR, Kiani S, Hashemizadeh S, Zarchi AS, Bosman A, Blue GM, Pahlavan S, Perry M, Orr Y, Mayorchak Y, Vandenberg J, Talkhabi M, Winlaw DS, Harvey RP, Aghdami N, Baharvand H. Fonoudi H, et al. Stem Cells Transl Med. 2015 Dec;4(12):1482-94. doi: 10.5966/sctm.2014-0275. Epub 2015 Oct 28. Stem Cells Transl Med. 2015. PMID: 26511653 Free PMC article.

3

hERG K(+) channels: structure, function, and clinical significance.

Vandenberg JI, Perry MD, Perrin MJ, Mann SA, Ke Y, Hill AP. Vandenberg JI, et al. Among authors: perry md. Physiol Rev. 2012 Jul;92(3):1393-478. doi: 10.1152/physrev.00036.2011. Physiol Rev. 2012. PMID: 22988594 Free article. Review.

4

TECRL: connecting sequence to consequence for a new sudden cardiac death gene.

Perry MD, Vandenberg JI. Perry MD, et al. EMBO Mol Med. 2016 Dec 1;8(12):1364-1365. doi: 10.15252/emmm.201606967. Print 2016 Dec. EMBO Mol Med. 2016. PMID: 27784710 Free PMC article.

5

Protocol-Dependent Differences in IC₅₀ Values Measured in Human Ether-Á-Go-Go-Related Gene Assays Occur in a Predictable Way and Can Be Used to Quantify State Preference of Drug Binding.

Lee W, Windley MJ, Perry MD, Vandenberg JI, Hill AP. Lee W, et al. Among authors: perry md. Mol Pharmacol. 2019 May;95(5):537-550. doi: 10.1124/mol.118.115220. Epub 2019 Feb 15. Mol Pharmacol. 2019. PMID: 30770456

6

High-throughput phenotyping of heteromeric human ether-à-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variants.

Ng CA, Perry MD, Liang W, Smith NJ, Foo B, Shrier A, Lukacs GL, Hill AP, Vandenberg JI. Ng CA, et al. Among authors: perry md. Heart Rhythm. 2020 Mar;17(3):492-500. doi: 10.1016/j.hrthm.2019.09.020. Epub 2019 Sep 23. Heart Rhythm. 2020. PMID: 31557540

7

Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization.

Perry MD, Ng CA, Mangala MM, Ng TYM, Hines AD, Liang W, Xu MJO, Hill AP, Vandenberg JI. Perry MD, et al. Cardiovasc Res. 2020 Jul 1;116(8):1434-1445. doi: 10.1093/cvr/cvz247. Cardiovasc Res. 2020. PMID: 31628797

8

Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events.

Ballouz S, Mangala MM, Perry MD, Heitmann S, Gillis JA, Hill AP, Vandenberg JI. Ballouz S, et al. Among authors: perry md. Cardiovasc Res. 2021 Aug 29;117(10):2216-2227. doi: 10.1093/cvr/cvaa280. Cardiovasc Res. 2021. PMID: 33002116 Free PMC article.

9

Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation.

TeBay C, McArthur JR, Mangala M, Kerr N, Heitmann S, Perry MD, Windley MJ, Vandenberg JI, Hill AP. TeBay C, et al. Among authors: perry md. Br J Pharmacol. 2022 Jun;179(11):2631-2646. doi: 10.1111/bph.15757. Epub 2022 Jan 27. Br J Pharmacol. 2022. PMID: 34837219 Free article.

10

Action Potential Morphology Accurately Predicts Proarrhythmic Risk for Drugs With Potential to Prolong Cardiac Repolarization.

Lee W, Ng B, Mangala MM, Perry MD, Subbiah RN, Vandenberg JI, Hill AP. Lee W, et al. Among authors: perry md. Circ Arrhythm Electrophysiol. 2023 Jul;16(7):399-410. doi: 10.1161/CIRCEP.122.011574. Epub 2023 Jun 19. Circ Arrhythm Electrophysiol. 2023. PMID: 37334695 Free article.

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