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Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler.
Laber S, Strobel S, Mercader JM, Dashti H, Dos Santos FRC, Kubitz P, Jackson M, Ainbinder A, Honecker J, Agrawal S, Garborcauskas G, Stirling DR, Leong A, Figueroa K, Sinnott-Armstrong N, Kost-Alimova M, Deodato G, Harney A, Way GP, Saadat A, Harken S, Reibe-Pal S, Ebert H, Zhang Y, Calabuig-Navarro V, McGonagle E, Stefek A, Dupuis J, Cimini BA, Hauner H, Udler MS, Carpenter AE, Florez JC, Lindgren C, Jacobs SBR, Claussnitzer M. Laber S, et al. Among authors: ainbinder a. Cell Genom. 2023 Jun 20;3(7):100346. doi: 10.1016/j.xgen.2023.100346. eCollection 2023 Jul 12. Cell Genom. 2023. PMID: 37492099 Free PMC article.
Adrenergic signaling regulates mitochondrial Ca2+ uptake through Pyk2-dependent tyrosine phosphorylation of the mitochondrial Ca2+ uniporter.
O-Uchi J, Jhun BS, Xu S, Hurst S, Raffaello A, Liu X, Yi B, Zhang H, Gross P, Mishra J, Ainbinder A, Kettlewell S, Smith GL, Dirksen RT, Wang W, Rizzuto R, Sheu SS. O-Uchi J, et al. Among authors: ainbinder a. Antioxid Redox Signal. 2014 Aug 20;21(6):863-79. doi: 10.1089/ars.2013.5394. Epub 2014 Jun 25. Antioxid Redox Signal. 2014. PMID: 24800979 Free PMC article.
AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation.
Lanner JT, Georgiou DK, Dagnino-Acosta A, Ainbinder A, Cheng Q, Joshi AD, Chen Z, Yarotskyy V, Oakes JM, Lee CS, Monroe TO, Santillan A, Dong K, Goodyear L, Ismailov II, Rodney GG, Dirksen RT, Hamilton SL. Lanner JT, et al. Among authors: ainbinder a. Nat Med. 2012 Jan 8;18(2):244-51. doi: 10.1038/nm.2598. Nat Med. 2012. PMID: 22231556 Free PMC article.