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Randomized placebo-controlled crossover study to assess tolerability and pharmacodynamics of zagociguat, a soluble guanylyl cyclase stimulator, in healthy elderly.
van Kraaij SJW, Borghans L, Klaassen ES, Gal P, van der Grond J, Tripp K, Winrow C, Glasser C, Groeneveld GJ. van Kraaij SJW, et al. Among authors: groeneveld gj. Br J Clin Pharmacol. 2023 Dec;89(12):3606-3617. doi: 10.1111/bcp.15861. Epub 2023 Aug 13. Br J Clin Pharmacol. 2023. PMID: 37488930 Clinical Trial.
Pharmacokinetics and pharmacodynamics of multiple doses of BG00010, a neurotrophic factor with anti-hyperalgesic effects, in patients with sciatica.
Okkerse P, Hay JL, Versage E, Tang Y, Galluppi G, Ravina B, Verma A, Williams L, Aycardi E, Groeneveld GJ. Okkerse P, et al. Among authors: groeneveld gj. Br J Clin Pharmacol. 2016 Jul;82(1):108-17. doi: 10.1111/bcp.12941. Epub 2016 May 13. Br J Clin Pharmacol. 2016. PMID: 27016000 Free PMC article. Clinical Trial.
Effects on Spasticity and Neuropathic Pain of an Oral Formulation of Δ9-tetrahydrocannabinol in Patients WithProgressive Multiple Sclerosis.
van Amerongen G, Kanhai K, Baakman AC, Heuberger J, Klaassen E, Beumer TL, Strijers RLM, Killestein J, van Gerven J, Cohen A, Groeneveld GJ. van Amerongen G, et al. Among authors: groeneveld gj. Clin Ther. 2018 Sep;40(9):1467-1482. doi: 10.1016/j.clinthera.2017.01.016. Epub 2017 Feb 9. Clin Ther. 2018. PMID: 28189366 Clinical Trial.
An anti-nicotinic cognitive challenge model using mecamylamine in comparison with the anti-muscarinic cognitive challenge using scopolamine.
Baakman AC, Alvarez-Jimenez R, Rissmann R, Klaassen ES, Stevens J, Goulooze SC, den Burger JCG, Swart EL, van Gerven JMA, Groeneveld GJ. Baakman AC, et al. Among authors: groeneveld gj. Br J Clin Pharmacol. 2017 Aug;83(8):1676-1687. doi: 10.1111/bcp.13268. Epub 2017 Apr 8. Br J Clin Pharmacol. 2017. PMID: 28217868 Free PMC article. Clinical Trial.
142 results