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Design and Discovery of Water-Soluble Benzooxaphosphole-Based Ligands for Hindered Suzuki-Miyaura Coupling Reactions with Low Catalyst Load.
Shada ADR, Mangunuru HPR, Terrab L, Tenneti S, Kalikinidi NR, Naini SR, Gajula P, Crull EB, Janganati V, Kovvuri R, Natarajan V, Lee D, Yin J, Samankumara L, Mahar R, Zhang X, Chen A, Hewa-Rahinduwage CC, Wang Z, Mamunooru M, Rana J, Wannere CS, Armstrong JD 3rd, Williamson RT, Sirasani G, Qu B, Senanayake CH. Shada ADR, et al. Among authors: sirasani g. Org Lett. 2024 Apr 12;26(14):2751-2757. doi: 10.1021/acs.orglett.3c01663. Epub 2023 Jul 24. Org Lett. 2024. PMID: 37486800
Application of Chiral Transfer Reagents to Improve Stereoselectivity and Yields in the Synthesis of the Antituberculosis Drug Bedaquiline.
Robey JMS, Maity S, Aleshire SL, Ghosh A, Yadaw AK, Roy S, Mear SJ, Jamison TF, Sirasani G, Senanayake CH, Stringham RW, Gupton BF, Donsbach KO, Nelson RC, Shanahan CS. Robey JMS, et al. Among authors: sirasani g. Org Process Res Dev. 2023 Oct 13;27(11):2146-2159. doi: 10.1021/acs.oprd.3c00287. eCollection 2023 Nov 17. Org Process Res Dev. 2023. PMID: 38025988 Free PMC article.
Synthesis of Chiral 1,2-Amino Alcohol-Containing Compounds Utilizing Ruthenium-Catalyzed Asymmetric Transfer Hydrogenation of Unprotected α-Ketoamines.
Mangunuru HPR, Terrab L, Janganati V, Kalikinidi NR, Tenneti S, Natarajan V, Shada ADR, Naini SR, Gajula P, Lee D, Samankumara LP, Mamunooru M, Jayaraman A, Sahani RL, Yin J, Hewa-Rahinduwage CC, Gangu A, Chen A, Wang Z, Desai B, Yue TY, Wannere CS, Armstrong JD 3rd, Donsbach KO, Sirasani G, Gupton BF, Qu B, Senanayake CH. Mangunuru HPR, et al. Among authors: sirasani g. J Org Chem. 2024 May 3;89(9):6085-6099. doi: 10.1021/acs.joc.4c00045. Epub 2024 Apr 22. J Org Chem. 2024. PMID: 38648720
Facile and Scalable Methodology for the Pyrrolo[2,1-f][1,2,4]triazine of Remdesivir.
Roy S, Yadaw A, Roy S, Sirasani G, Gangu A, Brown JD, Armstrong JD 3rd, Stringham RW, Gupton BF, Senanayake CH, Snead DR. Roy S, et al. Among authors: sirasani g. Org Process Res Dev. 2022 Jan 21;26(1):82-90. doi: 10.1021/acs.oprd.1c00071. Epub 2022 Jan 7. Org Process Res Dev. 2022. PMID: 35095258 Free PMC article. Review.
Toward a Practical, Nonenzymatic Process for Investigational COVID-19 Antiviral Molnupiravir from Cytidine: Supply-Centered Synthesis.
Gopalsamuthiram V, Kadam AL, Noble JK, Snead DR, Williams C, Jamison TF, Senanayake C, Yadaw AK, Roy S, Sirasani G, Gupton BF, Burns J, Cook DW, Stringham RW, Ahmad S, Krack R. Gopalsamuthiram V, et al. Among authors: sirasani g. Org Process Res Dev. 2021 Dec 17;25(12):2679-2685. doi: 10.1021/acs.oprd.1c00219. Epub 2021 Dec 9. Org Process Res Dev. 2021. PMID: 34955627 Free PMC article. Review.
Aspidosperma and Strychnos alkaloids: Chemistry and biology.
Zhao S, Sirasani G, Andrade RB. Zhao S, et al. Among authors: sirasani g. Alkaloids Chem Biol. 2021;86:1-143. doi: 10.1016/bs.alkal.2021.05.001. Epub 2021 Sep 21. Alkaloids Chem Biol. 2021. PMID: 34565505 Review.
Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication.
Munagala S, Sirasani G, Kokkonda P, Phadke M, Krynetskaia N, Lu P, Sharom FJ, Chaudhury S, Abdulhameed MD, Tawa G, Wallqvist A, Martinez R, Childers W, Abou-Gharbia M, Krynetskiy E, Andrade RB. Munagala S, et al. Among authors: sirasani g. Bioorg Med Chem. 2014 Feb 1;22(3):1148-55. doi: 10.1016/j.bmc.2013.12.022. Epub 2013 Dec 21. Bioorg Med Chem. 2014. PMID: 24405813
18 results