Kunos G - Search Results

1

A cortico-amygdala neural substrate for endocannabinoid modulation of fear extinction.

Gunduz-Cinar O, Castillo LI, Xia M, Van Leer E, Brockway ET, Pollack GA, Yasmin F, Bukalo O, Limoges A, Oreizi-Esfahani S, Kondev V, Báldi R, Dong A, Harvey-White J, Cinar R, Kunos G, Li Y, Zweifel LS, Patel S, Holmes A. Gunduz-Cinar O, et al. Among authors: kunos g. Neuron. 2023 Oct 4;111(19):3053-3067.e10. doi: 10.1016/j.neuron.2023.06.023. Epub 2023 Jul 21. Neuron. 2023. PMID: 37480845

2

The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics.

Mukhopadhyay B, Holovac K, Schuebel K, Mukhopadhyay P, Cinar R, Iyer S, Marietta C, Goldman D, Kunos G. Mukhopadhyay B, et al. Among authors: kunos g. Cell Death Discov. 2023 Mar 25;9(1):104. doi: 10.1038/s41420-023-01400-6. Cell Death Discov. 2023. PMID: 36966147 Free PMC article.

3

Cannabinoid receptor type 1 (CB₁R) inhibits hypothalamic leptin signaling via β-arrestin1 in complex with TC-PTP and STAT3.

Szanda G, Jourdan T, Wisniewski É, Cinar R, Godlewski G, Rajki A, Liu J, Chedester L, Szalai B, Tóth AD, Soltész-Katona E, Hunyady L, Inoue A, Horváth VB, Spät A, Tam J, Kunos G. Szanda G, et al. Among authors: kunos g. iScience. 2023 Jun 25;26(7):107207. doi: 10.1016/j.isci.2023.107207. eCollection 2023 Jul 21. iScience. 2023. PMID: 37534180 Free PMC article.

4

In vitro and in vivo pharmacokinetic characterization, chiral conversion and PBPK scaling towards human PK simulation of S-MRI-1867, a drug candidate for Hermansky-Pudlak syndrome pulmonary fibrosis.

Padilha EC, Yang M, Shah P, Wang AQ, Duan J, Park JK, Zawatsky CN, Malicdan MCV, Kunos G, Iyer MR, Gaucher G, Ravenelle F, Cinar R, Xu X. Padilha EC, et al. Among authors: kunos g. Biomed Pharmacother. 2023 Dec;168:115178. doi: 10.1016/j.biopha.2023.115178. Epub 2023 Oct 25. Biomed Pharmacother. 2023. PMID: 37890204 Free PMC article.

5

A human laboratory study on the link between alcohol administration and circulating fibroblast growth factor 21 (FGF21) in individuals with alcohol use disorder.

Farokhnia M, Wang T, Jourdan T, Godlewski G, Farinelli LA, Kunos G, Leggio L. Farokhnia M, et al. Among authors: kunos g. Drug Alcohol Depend. 2023 Apr 1;245:109809. doi: 10.1016/j.drugalcdep.2023.109809. Epub 2023 Feb 16. Drug Alcohol Depend. 2023. PMID: 36822122 Free PMC article.

6

A patient-based iPSC-derived hepatocyte model of alcohol-associated cirrhosis reveals bioenergetic insights into disease pathogenesis.

Mukhopadhyay B, Marietta C, Shen PH, Oiseni A, Mirshahi F, Mazzu M, Hodgkinson C, Winkler E, Yuan Q, Miranda D, Kunos G, Sanyal AJ, Goldman D. Mukhopadhyay B, et al. Among authors: kunos g. Nat Commun. 2024 May 1;15(1):2869. doi: 10.1038/s41467-024-47085-y. Nat Commun. 2024. PMID: 38693144 Free PMC article.

7

Alcohol-associated bowel disease: new insights into pathogenesis.

Maccioni L, Fu Y, Horsmans Y, Leclercq I, Stärkel P, Kunos G, Gao B. Maccioni L, et al. Among authors: kunos g. eGastroenterology. 2023 Jun;1(1):e100013. doi: 10.1136/egastro-2023-100013. Epub 2023 Aug 18. eGastroenterology. 2023. PMID: 37662449 Free PMC article.

8

Renal Mitochondrial ATP Transporter Ablation Ameliorates Obesity-Induced CKD.

Permyakova A, Hamad S, Hinden L, Baraghithy S, Kogot-Levin A, Yosef O, Shalev O, Tripathi MK, Amal H, Basu A, Arif M, Cinar R, Kunos G, Berger M, Leibowitz G, Tam J. Permyakova A, et al. Among authors: kunos g. J Am Soc Nephrol. 2024 Mar 1;35(3):281-298. doi: 10.1681/ASN.0000000000000294. Epub 2024 Jan 11. J Am Soc Nephrol. 2024. PMID: 38200648

9

Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models.

Feng D, Xiang X, Guan Y, Guillot A, Lu H, Chang C, He Y, Wang H, Pan H, Ju C, Colgan SP, Tacke F, Wang XW, Kunos G, Gao B. Feng D, et al. Among authors: kunos g. J Clin Invest. 2023 Aug 1;133(15):e166954. doi: 10.1172/JCI166954. J Clin Invest. 2023. PMID: 37338984 Free PMC article.

10

The effects of acute alcohol administration on circulating endocannabinoid levels in humans.

Sloan ME, Grant CW, Stangl BL, Klepp TD, Brewton HW, Cinar R, Kunos G, Ramchandani VA. Sloan ME, et al. Among authors: kunos g. Addict Biol. 2022 Sep;27(5):e13197. doi: 10.1111/adb.13197. Addict Biol. 2022. PMID: 36001429 Free PMC article. Clinical Trial.

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