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Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma.
Hansson K, Radke K, Aaltonen K, Saarela J, Mañas A, Sjölund J, Smith EM, Pietras K, Påhlman S, Wennerberg K, Gisselsson D, Bexell D. Hansson K, et al. Among authors: pahlman s. Sci Transl Med. 2020 Sep 23;12(562):eaba4434. doi: 10.1126/scitranslmed.aba4434. Sci Transl Med. 2020. PMID: 32967973
Inflammatory macrophage derived TNFα downregulates estrogen receptor α via FOXO3a inactivation in human breast cancer cells.
Gunnarsdóttir FB, Hagerling C, Bergenfelz C, Mehmeti M, Källberg E, Allaoui R, Mohlin S, Påhlman S, Larsson C, Jirström K, Bexell D, Leandersson K. Gunnarsdóttir FB, et al. Among authors: pahlman s. Exp Cell Res. 2020 May 1;390(1):111932. doi: 10.1016/j.yexcr.2020.111932. Epub 2020 Mar 4. Exp Cell Res. 2020. PMID: 32145253 Free article.
Integrative discovery of treatments for high-risk neuroblastoma.
Almstedt E, Elgendy R, Hekmati N, Rosén E, Wärn C, Olsen TK, Dyberg C, Doroszko M, Larsson I, Sundström A, Arsenian Henriksson M, Påhlman S, Bexell D, Vanlandewijck M, Kogner P, Jörnsten R, Krona C, Nelander S. Almstedt E, et al. Among authors: pahlman s. Nat Commun. 2020 Jan 3;11(1):71. doi: 10.1038/s41467-019-13817-8. Nat Commun. 2020. PMID: 31900415 Free PMC article.
ALK positively regulates MYCN activity through repression of HBP1 expression.
Claeys S, Denecker G, Durinck K, Decaesteker B, Mus LM, Loontiens S, Vanhauwaert S, Althoff K, Wigerup C, Bexell D, Dolman E, Henrich KO, Wehrmann L, Westerhout EM, Demoulin JB, Kumps C, Van Maerken T, Laureys G, Van Neste C, De Wilde B, De Wever O, Westermann F, Versteeg R, Molenaar JJ, Påhlman S, Schulte JH, De Preter K, Speleman F. Claeys S, et al. Among authors: pahlman s. Oncogene. 2019 Apr;38(15):2690-2705. doi: 10.1038/s41388-018-0595-3. Epub 2018 Dec 11. Oncogene. 2019. PMID: 30538293
Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma.
Braekeveldt N, von Stedingk K, Fransson S, Martinez-Monleon A, Lindgren D, Axelson H, Levander F, Willforss J, Hansson K, Øra I, Backman T, Börjesson A, Beckman S, Esfandyari J, Berbegall AP, Noguera R, Karlsson J, Koster J, Martinsson T, Gisselsson D, Påhlman S, Bexell D. Braekeveldt N, et al. Among authors: pahlman s. Cancer Res. 2018 Oct 15;78(20):5958-5969. doi: 10.1158/0008-5472.CAN-18-0527. Epub 2018 Aug 28. Cancer Res. 2018. PMID: 30154149
Promoter-associated proteins of EPAS1 identified by enChIP-MS - A putative role of HDX as a negative regulator.
Hamidian A, Vaapil M, von Stedingk K, Fujita T, Persson CU, Eriksson P, Veerla S, De Preter K, Speleman F, Fujii H, Påhlman S, Mohlin S. Hamidian A, et al. Among authors: pahlman s. Biochem Biophys Res Commun. 2018 May 5;499(2):291-298. doi: 10.1016/j.bbrc.2018.03.150. Epub 2018 Mar 26. Biochem Biophys Res Commun. 2018. PMID: 29577908 Free article.
186 results