Chook YM - Search Results

1

A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1.

Korff A, Yang X, O'Donovan K, Gonzalez A, Teubner BJ, Nakamura H, Messing J, Yang F, Carisey AF, Wang YD, Patni T, Sheppard H, Zakharenko SS, Chook YM, Taylor JP, Kim HJ. Korff A, et al. Among authors: chook ym. J Clin Invest. 2023 Jul 17;133(14):e160309. doi: 10.1172/JCI160309. J Clin Invest. 2023. PMID: 37463454 Free PMC article.

2

Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains.

Guo L, Kim HJ, Wang H, Monaghan J, Freyermuth F, Sung JC, O'Donovan K, Fare CM, Diaz Z, Singh N, Zhang ZC, Coughlin M, Sweeny EA, DeSantis ME, Jackrel ME, Rodell CB, Burdick JA, King OD, Gitler AD, Lagier-Tourenne C, Pandey UB, Chook YM, Taylor JP, Shorter J. Guo L, et al. Among authors: chook ym. Cell. 2018 Apr 19;173(3):677-692.e20. doi: 10.1016/j.cell.2018.03.002. Cell. 2018. PMID: 29677512 Free PMC article.

3

Mechanism of karyopherin-β2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).

Gonzalez A, Mannen T, Çağatay T, Fujiwara A, Matsumura H, Niesman AB, Brautigam CA, Chook YM, Yoshizawa T. Gonzalez A, et al. Among authors: chook ym. Sci Rep. 2021 Feb 12;11(1):3754. doi: 10.1038/s41598-021-83196-y. Sci Rep. 2021. PMID: 33580145 Free PMC article.

4

A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 is linked to neurodevelopmental disorders.

Gonzalez A, Kim HJ, Freibaum BD, Joyce Fung HY, Brautigam CA, Taylor JP, Chook YM. Gonzalez A, et al. Among authors: chook ym. bioRxiv [Preprint]. 2023 Jan 21:2023.01.20.524964. doi: 10.1101/2023.01.20.524964. bioRxiv. 2023. PMID: 36711837 Free PMC article. Updated. Preprint.

5

A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders.

Gonzalez A, Kim HJ, Freibaum BD, Fung HYJ, Brautigam CA, Taylor JP, Chook YM. Gonzalez A, et al. Among authors: chook ym. Structure. 2023 Aug 3;31(8):924-934.e4. doi: 10.1016/j.str.2023.05.010. Epub 2023 Jun 5. Structure. 2023. PMID: 37279758

6

Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS).

Zhang ZC, Chook YM. Zhang ZC, et al. Among authors: chook ym. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12017-21. doi: 10.1073/pnas.1207247109. Epub 2012 Jul 9. Proc Natl Acad Sci U S A. 2012. PMID: 22778397 Free PMC article.

7

pCRM1exportome: database of predicted CRM1-dependent Nuclear Export Signal (NES) motifs in cancer-related genes.

Lee Y, Baumhardt JM, Pei J, Chook YM, Grishin NV. Lee Y, et al. Among authors: chook ym. Bioinformatics. 2020 Feb 1;36(3):961-963. doi: 10.1093/bioinformatics/btz657. Bioinformatics. 2020. PMID: 31504173 Free PMC article.

8

Karyopherin-β2 Recognition of a PY-NLS Variant that Lacks the Proline-Tyrosine Motif.

Soniat M, Chook YM. Soniat M, et al. Among authors: chook ym. Structure. 2016 Oct 4;24(10):1802-1809. doi: 10.1016/j.str.2016.07.018. Epub 2016 Sep 8. Structure. 2016. PMID: 27618664 Free PMC article.

9

Nuclear import of histones.

Bernardes NE, Chook YM. Bernardes NE, et al. Among authors: chook ym. Biochem Soc Trans. 2020 Dec 18;48(6):2753-2767. doi: 10.1042/BST20200572. Biochem Soc Trans. 2020. PMID: 33300986 Free PMC article. Review.

10

Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1.

Zhang ZC, Satterly N, Fontoura BM, Chook YM. Zhang ZC, et al. Among authors: chook ym. Mol Biol Cell. 2011 Dec;22(23):4657-68. doi: 10.1091/mbc.E11-03-0222. Epub 2011 Sep 30. Mol Biol Cell. 2011. PMID: 21965294 Free PMC article.

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