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Characterization of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation.
Veverka V, Henry AJ, Slocombe PM, Ventom A, Mulloy B, Muskett FW, Muzylak M, Greenslade K, Moore A, Zhang L, Gong J, Qian X, Paszty C, Taylor RJ, Robinson MK, Carr MD. Veverka V, et al. Among authors: henry aj. J Biol Chem. 2009 Apr 17;284(16):10890-900. doi: 10.1074/jbc.M807994200. Epub 2009 Feb 10. J Biol Chem. 2009. PMID: 19208630 Free PMC article.
Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor.
Waters LC, Strong SL, Ferlemann E, Oka O, Muskett FW, Veverka V, Banerjee S, Schmedt T, Henry AJ, Klempnauer KH, Carr MD. Waters LC, et al. Among authors: henry aj. J Biol Chem. 2011 May 13;286(19):17270-80. doi: 10.1074/jbc.M110.166157. Epub 2011 Mar 16. J Biol Chem. 2011. PMID: 21454508 Free PMC article.
Automated protein-ligand interaction screening by mass spectrometry.
Maple HJ, Garlish RA, Rigau-Roca L, Porter J, Whitcombe I, Prosser CE, Kennedy J, Henry AJ, Taylor RJ, Crump MP, Crosby J. Maple HJ, et al. Among authors: henry aj. J Med Chem. 2012 Jan 26;55(2):837-51. doi: 10.1021/jm201347k. Epub 2012 Jan 12. J Med Chem. 2012. PMID: 22148839
Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors.
Holdsworth G, Slocombe P, Doyle C, Sweeney B, Veverka V, Le Riche K, Franklin RJ, Compson J, Brookings D, Turner J, Kennedy J, Garlish R, Shi J, Newnham L, McMillan D, Muzylak M, Carr MD, Henry AJ, Ceska T, Robinson MK. Holdsworth G, et al. Among authors: henry aj. J Biol Chem. 2012 Aug 3;287(32):26464-77. doi: 10.1074/jbc.M112.350108. Epub 2012 Jun 13. J Biol Chem. 2012. PMID: 22696217 Free PMC article.
The discovery, engineering and characterisation of a highly potent anti-human IL-13 fab fragment designed for administration by inhalation.
Lightwood D, O'Dowd V, Carrington B, Veverka V, Carr MD, Tservistas M, Henry AJ, Smith B, Tyson K, Lamour S, Bracher M, Sarkar K, Turner A, Lawson AD, Bourne T, Gozzard N, Palframan R. Lightwood D, et al. Among authors: henry aj. J Mol Biol. 2013 Feb 8;425(3):577-93. doi: 10.1016/j.jmb.2012.11.036. Epub 2012 Dec 3. J Mol Biol. 2013. PMID: 23219467
74 results