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Transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous system.
Gao Y, Wang Y, Chauss D, Villarino AV, Link VM, Nagashima H, Spinner CA, Koparde VN, Bouladoux N, Abers MS, Break TJ, Chopp LB, Park JH, Zhu J, Wiest DL, Leonard WJ, Lionakis MS, O'Shea JJ, Afzali B, Belkaid Y, Lazarevic V. Gao Y, et al. Among authors: park jh. Nat Immunol. 2023 Aug;24(8):1331-1344. doi: 10.1038/s41590-023-01553-7. Epub 2023 Jul 13. Nat Immunol. 2023. PMID: 37443284 Free PMC article.
Activated T cells secrete an alternatively spliced form of common γ-chain that inhibits cytokine signaling and exacerbates inflammation.
Hong C, Luckey MA, Ligons DL, Waickman AT, Park JY, Kim GY, Keller HR, Etzensperger R, Tai X, Lazarevic V, Feigenbaum L, Catalfamo M, Walsh ST, Park JH. Hong C, et al. Among authors: park jy, park jh. Immunity. 2014 Jun 19;40(6):910-23. doi: 10.1016/j.immuni.2014.04.020. Epub 2014 Jun 5. Immunity. 2014. PMID: 24909888 Free PMC article.
IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion.
Le Saout C, Luckey MA, Villarino AV, Smith M, Hasley RB, Myers TG, Imamichi H, Park JH, O'Shea JJ, Lane HC, Catalfamo M. Le Saout C, et al. Among authors: park jh. JCI Insight. 2017 Nov 16;2(22):e96228. doi: 10.1172/jci.insight.96228. eCollection 2017 Nov 16. JCI Insight. 2017. PMID: 29202461 Free PMC article.
Lessons learned: new insights on the role of cytokines in COVID-19.
Buszko M, Nita-Lazar A, Park JH, Schwartzberg PL, Verthelyi D, Young HA, Rosenberg AS. Buszko M, et al. Among authors: park jh. Nat Immunol. 2021 Apr;22(4):404-411. doi: 10.1038/s41590-021-00901-9. Nat Immunol. 2021. PMID: 33723418 Free PMC article.
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