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A clindamycin acetylated derivative with reduced antibacterial activity inhibits articular hyperalgesia and edema by attenuating neutrophil recruitment, NF-κB activation and tumor necrosis factor-α production.
Rodrigues FF, Lino CI, Oliveira VLS, Zaidan I, Melo ISF, Braga AV, Costa SOAM, Morais MI, Barbosa BCM, da Costa YFG, Moreira NF, Alves MS, Braga AD, Carneiro FS, Carvalho AFS, Queiroz-Junior CM, Sousa LP, Amaral FA, Oliveira RB, Coelho MM, Machado RR. Rodrigues FF, et al. Int Immunopharmacol. 2023 Sep;122:110609. doi: 10.1016/j.intimp.2023.110609. Epub 2023 Jul 8. Int Immunopharmacol. 2023. PMID: 37429145
Therapeutic treatment of Zika virus infection using a brain-penetrating antiviral peptide.
Jackman JA, Costa VV, Park S, Real ALCV, Park JH, Cardozo PL, Ferhan AR, Olmo IG, Moreira TP, Bambirra JL, Queiroz VF, Queiroz-Junior CM, Foureaux G, Souza DG, Ribeiro FM, Yoon BK, Wynendaele E, De Spiegeleer B, Teixeira MM, Cho NJ. Jackman JA, et al. Nat Mater. 2018 Nov;17(11):971-977. doi: 10.1038/s41563-018-0194-2. Epub 2018 Oct 22. Nat Mater. 2018. PMID: 30349030
In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy.
Camargos VN, Foureaux G, Medeiros DC, da Silveira VT, Queiroz-Junior CM, Matosinhos ALB, Figueiredo AFA, Sousa CDF, Moreira TP, Queiroz VF, Dias ACF, Santana KTO, Passos I, Real ALCV, Silva LC, Mourão FAG, Wnuk NT, Oliveira MAP, Macari S, Silva T, Garlet GP, Jackman JA, Soriani FM, Moraes MFD, Mendes EMAM, Ribeiro FM, Costa GMJ, Teixeira AL, Cho NJ, Oliveira ACP, Teixeira MM, Costa VV, Souza DG. Camargos VN, et al. EBioMedicine. 2019 Jun;44:516-529. doi: 10.1016/j.ebiom.2019.05.014. Epub 2019 May 23. EBioMedicine. 2019. PMID: 31130472 Free PMC article.
N-Methyl-d-Aspartate (NMDA) Receptor Blockade Prevents Neuronal Death Induced by Zika Virus Infection.
Costa VV, Del Sarto JL, Rocha RF, Silva FR, Doria JG, Olmo IG, Marques RE, Queiroz-Junior CM, Foureaux G, Araújo JMS, Cramer A, Real ALCV, Ribeiro LS, Sardi SI, Ferreira AJ, Machado FS, de Oliveira AC, Teixeira AL, Nakaya HI, Souza DG, Ribeiro FM, Teixeira MM. Costa VV, et al. mBio. 2017 Apr 25;8(2):e00350-17. doi: 10.1128/mBio.00350-17. mBio. 2017. PMID: 28442607 Free PMC article.
Lithothamnion muelleri treatment ameliorates inflammatory and hypernociceptive responses in antigen-induced arthritis in mice.
Costa VV, Amaral FA, Coelho FM, Queiroz-Junior CM, Malagoli BG, Gomes JH, Lopes F, Silveira KD, Sachs D, Fagundes CT, Tavares LD, Pinho V, Silva TA, Teixeira MM, Braga FC, Souza DG. Costa VV, et al. PLoS One. 2015 Mar 20;10(3):e0118356. doi: 10.1371/journal.pone.0118356. eCollection 2015. PLoS One. 2015. PMID: 25793994 Free PMC article.
121 results