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A clindamycin acetylated derivative with reduced antibacterial activity inhibits articular hyperalgesia and edema by attenuating neutrophil recruitment, NF-κB activation and tumor necrosis factor-α production.
Rodrigues FF, Lino CI, Oliveira VLS, Zaidan I, Melo ISF, Braga AV, Costa SOAM, Morais MI, Barbosa BCM, da Costa YFG, Moreira NF, Alves MS, Braga AD, Carneiro FS, Carvalho AFS, Queiroz-Junior CM, Sousa LP, Amaral FA, Oliveira RB, Coelho MM, Machado RR. Rodrigues FF, et al. Among authors: lino ci. Int Immunopharmacol. 2023 Sep;122:110609. doi: 10.1016/j.intimp.2023.110609. Epub 2023 Jul 8. Int Immunopharmacol. 2023. PMID: 37429145
Heterocycle Thiazole Compounds Exhibit Antifungal Activity through Increase in the Production of Reactive Oxygen Species in the Cryptococcus neoformans-Cryptococcus gattii Species Complex.
Sá NP, Lima CM, Lino CI, Barbeira PJS, Baltazar LM, Santos DA, Oliveira RB, Mylonakis E, Fuchs BB, Johann S. Sá NP, et al. Among authors: lino ci. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e02700-16. doi: 10.1128/AAC.02700-16. Print 2017 Aug. Antimicrob Agents Chemother. 2017. PMID: 28533240 Free PMC article.
In vivo and in vitro activity of a bis-arylidenecyclo-alkanone against fluconazole-susceptible and -resistant isolates of Candida albicans.
de Sá NP, de Paula LFJ, Lopes LFF, Cruz LIB, Matos TTS, Lino CI, de Oliveira RB, de Souza-Fagundes EM, Fuchs BB, Mylonakis E, Johann S. de Sá NP, et al. Among authors: lino ci. J Glob Antimicrob Resist. 2018 Sep;14:287-293. doi: 10.1016/j.jgar.2018.04.012. Epub 2018 Apr 30. J Glob Antimicrob Resist. 2018. PMID: 29715565