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A clindamycin acetylated derivative with reduced antibacterial activity inhibits articular hyperalgesia and edema by attenuating neutrophil recruitment, NF-κB activation and tumor necrosis factor-α production.
Rodrigues FF, Lino CI, Oliveira VLS, Zaidan I, Melo ISF, Braga AV, Costa SOAM, Morais MI, Barbosa BCM, da Costa YFG, Moreira NF, Alves MS, Braga AD, Carneiro FS, Carvalho AFS, Queiroz-Junior CM, Sousa LP, Amaral FA, Oliveira RB, Coelho MM, Machado RR. Rodrigues FF, et al. Among authors: braga av. Int Immunopharmacol. 2023 Sep;122:110609. doi: 10.1016/j.intimp.2023.110609. Epub 2023 Jul 8. Int Immunopharmacol. 2023. PMID: 37429145
4-Methylbenzenecarbothioamide, a hydrogen sulfide donor, inhibits tumor necrosis factor-α and CXCL1 production and exhibits activity in models of pain and inflammation.
Melo ISF, Rodrigues FF, Costa SOAM, Braga AV, Morais MÍ, Vaz JA, Neto LS, Galvão I, Modolo LV, Amaral FA, Oliveira RB, de Fátima Â, Coelho MM, Machado RR. Melo ISF, et al. Among authors: braga av. Eur J Pharmacol. 2019 Aug 5;856:172404. doi: 10.1016/j.ejphar.2019.172404. Epub 2019 May 24. Eur J Pharmacol. 2019. PMID: 31132352 Free article.
Metformin antinociceptive effect in models of nociceptive and neuropathic pain is partially mediated by activation of opioidergic mechanisms.
Augusto PSA, Braga AV, Rodrigues FF, Morais MI, Dutra MMGB, Batista CRA, Melo ISF, Costa SOAM, Goulart FA, Coelho MM, Machado RR. Augusto PSA, et al. Among authors: braga av. Eur J Pharmacol. 2019 Sep 5;858:172497. doi: 10.1016/j.ejphar.2019.172497. Epub 2019 Jun 22. Eur J Pharmacol. 2019. PMID: 31238066 Free article.
Electrochemical evidence of nitrate release from the nitrooxy compound 4-((nitrooxy) methyl)-3-nitrobenzoic acid and its antinociceptive and anti-inflammatory activities in mice.
Braga AV, da Silva RRL, Rodrigues IB, Marques GVL, Xavier AFA, Boane A, Paiva MRB, Franco PHC, Rodrigues FF, Melo ISF, Silva Cunha Júnior AD, César IDC, Goulart MOF, Oliveira RB, Coelho MM, Machado RR. Braga AV, et al. Biomed Pharmacother. 2021 Jan;133:110913. doi: 10.1016/j.biopha.2020.110913. Epub 2020 Nov 27. Biomed Pharmacother. 2021. PMID: 33249284 Free article.
Metformin effect in models of inflammation is associated with activation of ATP-dependent potassium channels and inhibition of tumor necrosis factor-α production.
Augusto PSA, Matsui TC, Braga AV, Rodrigues FF, Morais MI, Dutra MMGB, Batista CRA, Melo ISF, Costa SOAM, Bertollo CM, Coelho MM, Machado RR. Augusto PSA, et al. Among authors: braga av. Inflammopharmacology. 2022 Feb;30(1):233-241. doi: 10.1007/s10787-021-00899-4. Epub 2021 Nov 30. Inflammopharmacology. 2022. PMID: 34850313
RI75, a curcumin analogue, inhibits tumor necrosis factor-α and interleukin-6 production and exhibits antiallodynic and antiedematogenic activities in mice.
Costa SOAM, Rodrigues IB, Braga AV, Barbosa BCM, Silva RRL, Rodrigues FF, Melo ISF, Morais MÍ, Castro BFM, Júnior ASC, Maltarollo VG, Oliveira RB, Coelho MM, Machado RR. Costa SOAM, et al. Among authors: braga av. Inflammopharmacology. 2022 Apr;30(2):505-515. doi: 10.1007/s10787-021-00913-9. Epub 2022 Jan 30. Inflammopharmacology. 2022. PMID: 35094257
Campomanesia lineatifolia Ruiz & Pavón (Myrtaceae): Isolation of major and minor compounds of phenolic-rich extract by high-speed countercurrent chromatography and anti-inflammatory evaluation.
Neves NCV, de Mello MP, Zaidan I, Sousa LP, Braga AV, Machado RR, Kukula-Koch W, Boylan F, Caliari MV, Castilho RO. Neves NCV, et al. Among authors: braga av. J Ethnopharmacol. 2023 Jun 28;310:116417. doi: 10.1016/j.jep.2023.116417. Epub 2023 Mar 28. J Ethnopharmacol. 2023. PMID: 36990302
20 results