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A phase 1/2 study of azacitidine, venetoclax and pevonedistat in newly diagnosed secondary AML and in MDS or CMML after failure of hypomethylating agents.
Short NJ, Muftuoglu M, Ong F, Nasr L, Macaron W, Montalban-Bravo G, Alvarado Y, Basyal M, Daver N, Dinardo CD, Borthakur G, Jain N, Ohanian M, Jabbour E, Issa GC, Qiao W, Huang X, Kanagal-Shamanna R, Patel KP, Bose P, Ravandi F, Delumpa R, Abramova R, Garcia-Manero G, Andreeff M, Cortes J, Kantarjian H. Short NJ, et al. Among authors: issa gc. J Hematol Oncol. 2023 Jul 8;16(1):73. doi: 10.1186/s13045-023-01476-8. J Hematol Oncol. 2023. PMID: 37422688 Free PMC article. Clinical Trial.
BET bromodomain inhibition as a therapeutic strategy to target c-Myc.
Delmore JE, Issa GC, Lemieux ME, Rahl PB, Shi J, Jacobs HM, Kastritis E, Gilpatrick T, Paranal RM, Qi J, Chesi M, Schinzel AC, McKeown MR, Heffernan TP, Vakoc CR, Bergsagel PL, Ghobrial IM, Richardson PG, Young RA, Hahn WC, Anderson KC, Kung AL, Bradner JE, Mitsiades CS. Delmore JE, et al. Among authors: issa gc. Cell. 2011 Sep 16;146(6):904-17. doi: 10.1016/j.cell.2011.08.017. Epub 2011 Sep 1. Cell. 2011. PMID: 21889194 Free PMC article.
Key role of microRNAs in Waldenström's macroglobulinemia pathogenesis.
Sacco A, Maiso P, Azab A, Azab F, Zhang Y, Liu Y, Ngo HT, Morgan B, Quang P, Issa G, Ghobrial IM, Roccaro AM. Sacco A, et al. Clin Lymphoma Myeloma Leuk. 2011 Feb;11(1):109-11. doi: 10.3816/CLML.2011.n.022. Clin Lymphoma Myeloma Leuk. 2011. PMID: 21454206
The bone marrow niche in Waldenström's macroglobulinemia.
Ghobrial IM, Zhang Y, Liu Y, Ngo H, Azab F, Sacco A, Azab A, Maiso P, Morgan B, Quang P, Issa G, Roccaro A. Ghobrial IM, et al. Clin Lymphoma Myeloma Leuk. 2011 Feb;11(1):118-20. doi: 10.3816/CLML.2011.n.025. Clin Lymphoma Myeloma Leuk. 2011. PMID: 21454209 Review.
Novel agents in Waldenström macroglobulinemia.
Issa GC, Ghobrial IM, Roccaro AM. Issa GC, et al. Clin Investig (Lond). 2011;1(6):815-824. doi: 10.4155/CLI.11.60. Clin Investig (Lond). 2011. PMID: 22034589 Free PMC article.
Targeting the bone marrow in Waldenstrom macroglobulinemia.
Ghobrial IM, Zhang Y, Liu Y, Ngo H, Azab F, Sacco A, Azab A, Maiso P, Morgan B, Quang P, Issa GC, Leleu X, Roccaro AM. Ghobrial IM, et al. Among authors: issa gc. Clin Lymphoma Myeloma Leuk. 2011 Jun;11 Suppl 1(Suppl 1):S65-9. doi: 10.1016/j.clml.2011.03.022. Epub 2011 Apr 30. Clin Lymphoma Myeloma Leuk. 2011. PMID: 22035751 Free PMC article. Review.
Hyper-CVAD plus ponatinib versus hyper-CVAD plus dasatinib as frontline therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: A propensity score analysis.
Sasaki K, Jabbour EJ, Ravandi F, Short NJ, Thomas DA, Garcia-Manero G, Daver NG, Kadia TM, Konopleva MY, Jain N, Issa GC, Jeanis V, Moore HG, Garris RS, Pemmaraju N, Cortes JE, O'Brien SM, Kantarjian HM. Sasaki K, et al. Among authors: issa gc. Cancer. 2016 Dec 1;122(23):3650-3656. doi: 10.1002/cncr.30231. Epub 2016 Aug 1. Cancer. 2016. PMID: 27479888 Free PMC article. Clinical Trial.
Prognostic significance of day 14 bone marrow evaluation in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia.
Short NJ, Kantarjian HM, Sasaki K, Cortes JE, Ravandi F, Thomas DA, Garcia-Manero G, Khouri I, Kebriaei P, Champlin RE, Pierce S, Issa GC, Konopleva M, Kadia TM, Bueso-Ramos C, Khoury JD, Jain N, O'Brien SM, Jabbour E. Short NJ, et al. Among authors: issa gc. Cancer. 2016 Dec 15;122(24):3812-3820. doi: 10.1002/cncr.30262. Epub 2016 Aug 10. Cancer. 2016. PMID: 27508525 Free PMC article.
128 results