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Endogenous Nampt upregulation is associated with diabetic nephropathy inflammatory-fibrosis through the NF-κB p65 and Sirt1 pathway; NMN alleviates diabetic nephropathy inflammatory-fibrosis by inhibiting endogenous Nampt.
Chen Y, Liang Y, Hu T, Wei R, Cai C, Wang P, Wang L, Qiao W, Feng L. Chen Y, et al. Among authors: wang l, wang p. Exp Ther Med. 2017 Nov;14(5):4181-4193. doi: 10.3892/etm.2017.5098. Epub 2017 Sep 1. Exp Ther Med. 2017. PMID: 29104634 Free PMC article.
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