Cappell SD - Search Results

1

Loss of CDK4/6 activity in S/G2 phase leads to cell cycle reversal.

Cornwell JA, Crncec A, Afifi MM, Tang K, Amin R, Cappell SD. Cornwell JA, et al. Among authors: cappell sd. Nature. 2023 Jul;619(7969):363-370. doi: 10.1038/s41586-023-06274-3. Epub 2023 Jul 5. Nature. 2023. PMID: 37407814 Free PMC article.

2

Cell cycle-dependent phosphorylation and ubiquitination of a G protein alpha subunit.

Torres MP, Clement ST, Cappell SD, Dohlman HG. Torres MP, et al. Among authors: cappell sd. J Biol Chem. 2011 Jun 10;286(23):20208-16. doi: 10.1074/jbc.M111.239343. Epub 2011 Apr 26. J Biol Chem. 2011. PMID: 21521692 Free PMC article.

3

EMI1 switches from being a substrate to an inhibitor of APC/C^CDH1 to start the cell cycle.

Cappell SD, Mark KG, Garbett D, Pack LR, Rape M, Meyer T. Cappell SD, et al. Nature. 2018 Jun;558(7709):313-317. doi: 10.1038/s41586-018-0199-7. Epub 2018 Jun 6. Nature. 2018. PMID: 29875408 Free PMC article.

4

Cell cycle inertia underlies a bifurcation in cell fates after DNA damage.

Nathans JF, Cornwell JA, Afifi MM, Paul D, Cappell SD. Nathans JF, et al. Among authors: cappell sd. Sci Adv. 2021 Jan 13;7(3):eabe3882. doi: 10.1126/sciadv.abe3882. Print 2021 Jan. Sci Adv. 2021. PMID: 33523889 Free PMC article.

5

Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response.

Amin R, Shukla A, Zhu JJ, Kim S, Wang P, Tian SZ, Tran AD, Paul D, Cappell SD, Burkett S, Liu H, Lee MP, Kruhlak MJ, Dwyer JE, Simpson RM, Hager GL, Ruan Y, Hunter KW. Amin R, et al. Among authors: cappell sd. Nat Commun. 2021 Dec 13;12(1):7216. doi: 10.1038/s41467-021-27451-w. Nat Commun. 2021. PMID: 34903738 Free PMC article.

6

Revealing β-TrCP activity dynamics in live cells with a genetically encoded biosensor.

Paul D, Kales SC, Cornwell JA, Afifi MM, Rai G, Zakharov A, Simeonov A, Cappell SD. Paul D, et al. Among authors: cappell sd. Nat Commun. 2022 Oct 26;13(1):6364. doi: 10.1038/s41467-022-33762-3. Nat Commun. 2022. PMID: 36289220 Free PMC article.

7

Irreversible cell cycle exit associated with senescence is mediated by constitutive MYC degradation.

Afifi MM, Crncec A, Cornwell JA, Cataisson C, Paul D, Ghorab LM, Hernandez MO, Wong M, Kedei N, Cappell SD. Afifi MM, et al. Among authors: cappell sd. Cell Rep. 2023 Sep 26;42(9):113079. doi: 10.1016/j.celrep.2023.113079. Epub 2023 Aug 31. Cell Rep. 2023. PMID: 37656618 Free PMC article.

8

Transient Hysteresis in CDK4/6 Activity Underlies Passage of the Restriction Point in G1.

Chung M, Liu C, Yang HW, Köberlin MS, Cappell SD, Meyer T. Chung M, et al. Among authors: cappell sd. Mol Cell. 2019 Nov 21;76(4):562-573.e4. doi: 10.1016/j.molcel.2019.08.020. Epub 2019 Sep 19. Mol Cell. 2019. PMID: 31543423 Free PMC article.

9

The RepID-CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation.

Jang SM, Nathans JF, Fu H, Redon CE, Jenkins LM, Thakur BL, Pongor LS, Baris AM, Gross JM, OʹNeill MJ, Indig FE, Cappell SD, Aladjem MI. Jang SM, et al. Among authors: cappell sd. Nat Commun. 2020 Jan 7;11(1):24. doi: 10.1038/s41467-019-13808-9. Nat Commun. 2020. PMID: 31911655 Free PMC article.

10

Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation.

Yang HW, Cappell SD, Jaimovich A, Liu C, Chung M, Daigh LH, Pack LR, Fan Y, Regot S, Covert M, Meyer T. Yang HW, et al. Among authors: cappell sd. Elife. 2020 Apr 7;9:e44571. doi: 10.7554/eLife.44571. Elife. 2020. PMID: 32255427 Free PMC article.

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