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Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation.
Calcagni' A, Staiano L, Zampelli N, Minopoli N, Herz NJ, Di Tullio G, Huynh T, Monfregola J, Esposito A, Cirillo C, Bajic A, Zahabiyon M, Curnock R, Polishchuk E, Parkitny L, Medina DL, Pastore N, Cullen PJ, Parenti G, De Matteis MA, Grumati P, Ballabio A. Calcagni' A, et al. Among authors: curnock r. Nat Commun. 2023 Jul 3;14(1):3911. doi: 10.1038/s41467-023-39643-7. Nat Commun. 2023. PMID: 37400440 Free PMC article.
TFEB-dependent lysosome biogenesis is required for senescence.
Curnock R, Yalci K, Palmfeldt J, Jäättelä M, Liu B, Carroll B. Curnock R, et al. EMBO J. 2023 May 2;42(9):e111241. doi: 10.15252/embj.2022111241. Epub 2023 Mar 27. EMBO J. 2023. PMID: 36970883 Free PMC article.
Age at gluten introduction and risk of celiac disease.
Aronsson CA, Lee HS, Liu E, Uusitalo U, Hummel S, Yang J, Hummel M, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Krischer J, Virtanen SM, Norris JM, Agardh D; TEDDY STUDY GROUP. Aronsson CA, et al. Pediatrics. 2015 Feb;135(2):239-45. doi: 10.1542/peds.2014-1787. Epub 2015 Jan 19. Pediatrics. 2015. PMID: 25601977 Free PMC article.
Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes.
Kemppainen KM, Ardissone AN, Davis-Richardson AG, Fagen JR, Gano KA, León-Novelo LG, Vehik K, Casella G, Simell O, Ziegler AG, Rewers MJ, Lernmark Å, Hagopian W, She JX, Krischer JP, Akolkar B, Schatz DA, Atkinson MA, Triplett EW; TEDDY Study Group. Kemppainen KM, et al. Diabetes Care. 2015 Feb;38(2):329-32. doi: 10.2337/dc14-0850. Epub 2014 Dec 17. Diabetes Care. 2015. PMID: 25519450 Free PMC article.
Risk of pediatric celiac disease according to HLA haplotype and country.
Liu E, Lee HS, Aronsson CA, Hagopian WA, Koletzko S, Rewers MJ, Eisenbarth GS, Bingley PJ, Bonifacio E, Simell V, Agardh D; TEDDY Study Group. Liu E, et al. N Engl J Med. 2014 Jul 3;371(1):42-9. doi: 10.1056/NEJMoa1313977. N Engl J Med. 2014. PMID: 24988556 Free PMC article.
19 results