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In vivo evolution of a Klebsiella pneumoniae capsule defect promotes complement-mediated opsono-phagocytosis and persistence during recurrent infection.
Bain W, Ahn B, Peñaloza HF, McElheny CL, Tolman N, van der Geest R, Gonzalez-Ferrer S, Chen N, An X, Hosuru R, Tabary M, Papke E, Kohli N, Farooq N, Bachman W, Olonisakin TF, Xiong Z, Griffith MP, Sullivan M, Franks J, Mustapha MM, Iovleva A, Suber T, Shanks RQ, Ferreira VP, Stolz DB, Van Tyne D, Doi Y, Lee JS. Bain W, et al. Among authors: van der geest r, van tyne d. bioRxiv [Preprint]. 2023 Jun 1:2023.05.31.542722. doi: 10.1101/2023.05.31.542722. bioRxiv. 2023. PMID: 37398264 Free PMC article. Updated. Preprint.
Increased Alternative Complement Pathway Function and Improved Survival during Critical Illness.
Bain W, Li H, van der Geest R, Moore SR, Olonisakin TF, Ahn B, Papke E, Moghbeli K, DeSensi R, Rapport S, Saul M, Hulver M, Xiong Z, Mallampalli RK, Ray P, Morris A, Ma L, Doi Y, Zhang Y, Kitsios GD, Kulkarni HS, McVerry BJ, Ferreira VP, Nouraie M, Lee JS. Bain W, et al. Among authors: van der geest r. Am J Respir Crit Care Med. 2020 Jul 15;202(2):230-240. doi: 10.1164/rccm.201910-2083OC. Am J Respir Crit Care Med. 2020. PMID: 32374177 Free PMC article.
Lower respiratory tract myeloid cells harbor SARS-CoV-2 and display an inflammatory phenotype.
Bain W, Penaloza HF, Ladinsky MS, van der Geest R, Sullivan M, Ross M, Kitsios GD, Methe B, McVerry BJ, Morris A, Watson AM, Watkins SC, St Croix CM, Stolz DB, Bjorkman PJ, Lee JS. Bain W, et al. Among authors: van der geest r. medRxiv [Preprint]. 2020 Aug 14:2020.08.11.20171967. doi: 10.1101/2020.08.11.20171967. medRxiv. 2020. PMID: 32817968 Free PMC article. Updated. Preprint.
Stressed erythrophagocytosis induces immunosuppression during sepsis through heme-mediated STAT1 dysregulation.
Olonisakin TF, Suber T, Gonzalez-Ferrer S, Xiong Z, Peñaloza HF, van der Geest R, Xiong Y, Osei-Hwedieh DO, Tejero J, Rosengart MR, Mars WM, Van Tyne D, Perlegas A, Brashears S, Kim-Shapiro DB, Gladwin MT, Bachman MA, Hod EA, St Croix C, Tyurina YY, Kagan VE, Mallampalli RK, Ray A, Ray P, Lee JS. Olonisakin TF, et al. Among authors: van der geest r, van tyne d. J Clin Invest. 2021 Jan 4;131(1):e137468. doi: 10.1172/JCI137468. J Clin Invest. 2021. PMID: 32941182 Free PMC article.
Lower Respiratory Tract Myeloid Cells Harbor SARS-Cov-2 and Display an Inflammatory Phenotype.
Bain WG, Peñaloza HF, Ladinsky MS, van der Geest R, Sullivan M, Ross M, Kitsios GD, Methé BA, McVerry BJ, Morris A, Watson AM, Watkins SC, St Croix CM, Stolz DB, Bjorkman PJ, Lee JS. Bain WG, et al. Among authors: van der geest r. Chest. 2021 Mar;159(3):963-966. doi: 10.1016/j.chest.2020.10.083. Epub 2020 Nov 18. Chest. 2021. PMID: 33217417 Free PMC article. No abstract available.
Interleukin-36 Cytokines in Infectious and Non-Infectious Lung Diseases.
Peñaloza HF, van der Geest R, Ybe JA, Standiford TJ, Lee JS. Peñaloza HF, et al. Among authors: van der geest r. Front Immunol. 2021 Nov 23;12:754702. doi: 10.3389/fimmu.2021.754702. eCollection 2021. Front Immunol. 2021. PMID: 34887860 Free PMC article. Review.
BATF2 enhances proinflammatory cytokine responses in macrophages and improves early host defense against pulmonary Klebsiella pneumoniae infection.
van der Geest R, Peñaloza HF, Xiong Z, Gonzalez-Ferrer S, An X, Li H, Fan H, Tabary M, Nouraie SM, Zhao Y, Zhang Y, Chen K, Alder JK, Bain WG, Lee JS. van der Geest R, et al. Am J Physiol Lung Cell Mol Physiol. 2023 Nov 1;325(5):L604-L616. doi: 10.1152/ajplung.00441.2022. Epub 2023 Sep 19. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37724373
In vivo evolution of a Klebsiella pneumoniae capsule defect with wcaJ mutation promotes complement-mediated opsono-phagocytosis during recurrent infection.
Bain W, Ahn B, Peñaloza HF, McElheny CL, Tolman N, van der Geest R, Gonzalez-Ferrer S, Chen N, An X, Hosuru R, Tabary M, Papke E, Kohli N, Farooq N, Bachman W, Olonisakin TF, Xiong Z, Griffith MP, Sullivan M, Franks J, Mustapha MM, Iovleva A, Suber T, Shanks RQ, Ferreira VP, Stolz DB, Van Tyne D, Doi Y, Lee JS. Bain W, et al. Among authors: van der geest r. J Infect Dis. 2024 Jan 25:jiae003. doi: 10.1093/infdis/jiae003. Online ahead of print. J Infect Dis. 2024. PMID: 38271564
386 results