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Page 1
Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity.
Zhang L, Butler CR, Maresca KP, Takano A, Nag S, Jia Z, Arakawa R, Piro JR, Samad T, Smith DL, Nason DM, O'Neil S, McAllister L, Schildknegt K, Trapa P, McCarthy TJ, Villalobos A, Halldin C. Zhang L, et al. Among authors: maresca kp. J Med Chem. 2019 Sep 26;62(18):8532-8543. doi: 10.1021/acs.jmedchem.9b00847. Epub 2019 Sep 16. J Med Chem. 2019. PMID: 31483137
First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B.
Wakabayashi Y, Stenkrona P, Arakawa R, Yan X, Van Buskirk MG, Jenkins MD, Santamaria JAM, Maresca KP, Takano A, Liow JS, Chappie TA, Varrone A, Nag S, Zhang L, Hughes ZA, Schmidt CJ, Doran SD, Mannes A, Zanotti-Fregonara P, Ooms M, Morse CL, Zoghbi SS, Halldin C, Pike VW, Innis RB. Wakabayashi Y, et al. Among authors: maresca kp. J Nucl Med. 2022 Dec;63(12):1919-1924. doi: 10.2967/jnumed.122.263838. Epub 2022 Jun 30. J Nucl Med. 2022. PMID: 35772961 Free PMC article.
Target occupancy study and whole-body dosimetry with a MAGL PET ligand [11C]PF-06809247 in non-human primates.
Arakawa R, Takano A, Nag S, Jia Z, Amini N, Maresca KP, Zhang L, Keliher EJ, Butler CR, Piro JR, Samad TA, Smith D, Nason D, O'Neil S, Trapa P, Fonseca KR, Litchfield J, McCarthy T, Carson RE, Halldin C. Arakawa R, et al. Among authors: maresca kp. EJNMMI Res. 2022 Mar 4;12(1):13. doi: 10.1186/s13550-022-00882-2. EJNMMI Res. 2022. PMID: 35244788 Free PMC article.
Brain Penetration of the ROS1/ALK Inhibitor Lorlatinib Confirmed by PET.
Collier TL, Maresca KP, Normandin MD, Richardson P, McCarthy TJ, Liang SH, Waterhouse RN, Vasdev N. Collier TL, et al. Among authors: maresca kp. Mol Imaging. 2017 Jan-Dec;16:1536012117736669. doi: 10.1177/1536012117736669. Mol Imaging. 2017. PMID: 29067878 Free PMC article.
Preclinical Evaluation of 89Zr-Df-IAB22M2C PET as an Imaging Biomarker for the Development of the GUCY2C-CD3 Bispecific PF-07062119 as a T Cell Engaging Therapy.
Maresca KP, Chen J, Mathur D, Giddabasappa A, Root A, Narula J, King L, Schaer D, Golas J, Kobylarz K, Rosfjord E, Keliher E, Chen L, Ram S, Pickering EH, Hardwick JS, Rejto PA, Hussein A, Ilovich O, Staton K, Wilson I, McCarthy TJ. Maresca KP, et al. Mol Imaging Biol. 2021 Dec;23(6):941-951. doi: 10.1007/s11307-021-01621-0. Epub 2021 Jun 18. Mol Imaging Biol. 2021. PMID: 34143379 Free PMC article.
Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis.
McClure KF, Piotrowski DW, Petersen D, Wei L, Xiao J, Londregan AT, Kamlet AS, Dechert-Schmitt AM, Raymer B, Ruggeri RB, Canterbury D, Limberakis C, Liras S, DaSilva-Jardine P, Dullea RG, Loria PM, Reidich B, Salatto CT, Eng H, Kimoto E, Atkinson K, King-Ahmad A, Scott D, Beaumont K, Chabot JR, Bolt MW, Maresca K, Dahl K, Arakawa R, Takano A, Halldin C. McClure KF, et al. Among authors: maresca k. Angew Chem Int Ed Engl. 2017 Dec 18;56(51):16218-16222. doi: 10.1002/anie.201708744. Epub 2017 Nov 24. Angew Chem Int Ed Engl. 2017. PMID: 29073340
An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo.
Wang C, Keliher E, Zeller MWG, Wojtkiewicz GR, Aguirre AD, Buckbinder L, Kim HY, Chen J, Maresca K, Ahmed MS, Motlagh NJ, Nahrendorf M, Chen JW. Wang C, et al. Among authors: maresca k. Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11966-11971. doi: 10.1073/pnas.1818434116. Epub 2019 May 23. Proc Natl Acad Sci U S A. 2019. PMID: 31123149 Free PMC article.
Preclinical evaluation of an 131I-labeled benzamide for targeted radiotherapy of metastatic melanoma.
Joyal JL, Barrett JA, Marquis JC, Chen J, Hillier SM, Maresca KP, Boyd M, Gage K, Nimmagadda S, Kronauge JF, Friebe M, Dinkelborg L, Stubbs JB, Stabin MG, Mairs R, Pomper MG, Babich JW. Joyal JL, et al. Among authors: maresca kp. Cancer Res. 2010 May 15;70(10):4045-53. doi: 10.1158/0008-5472.CAN-09-4414. Epub 2010 May 4. Cancer Res. 2010. PMID: 20442292 Free PMC article.
46 results