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Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain.
Zhang L, Chen L, Dutra JK, Beck EM, Nag S, Takano A, Amini N, Arakawa R, Brodney MA, Buzon LM, Doran SD, Lanyon LF, McCarthy TJ, Bales KR, Nolan CE, O'Neill BT, Schildknegt K, Halldin C, Villalobos A. Zhang L, et al. Among authors: arakawa r. J Med Chem. 2018 Apr 26;61(8):3296-3308. doi: 10.1021/acs.jmedchem.7b01769. Epub 2018 Feb 2. J Med Chem. 2018. PMID: 29356535
Quantitative Analysis of 18F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate Brain.
Takano A, Chen L, Nag S, Brodney MA, Arakawa R, Chang C, Amini N, Doran SD, Dutra JK, McCarthy TJ, Nolan CE, O'Neill BT, Villalobos A, Zhang L, Halldin C. Takano A, et al. Among authors: arakawa r. J Nucl Med. 2019 Jul;60(7):992-997. doi: 10.2967/jnumed.118.217372. Epub 2018 Dec 7. J Nucl Med. 2019. PMID: 30530832 Free article.
Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity.
Zhang L, Butler CR, Maresca KP, Takano A, Nag S, Jia Z, Arakawa R, Piro JR, Samad T, Smith DL, Nason DM, O'Neil S, McAllister L, Schildknegt K, Trapa P, McCarthy TJ, Villalobos A, Halldin C. Zhang L, et al. Among authors: arakawa r. J Med Chem. 2019 Sep 26;62(18):8532-8543. doi: 10.1021/acs.jmedchem.9b00847. Epub 2019 Sep 16. J Med Chem. 2019. PMID: 31483137
PET imaging of beta-secretase 1 in the human brain: radiation dosimetry, quantification, and test-retest examination of [18F]PF-06684511.
Arakawa R, Takano A, Stenkrona P, Stepanov V, Nag S, Jahan M, Grybäck P, Bolin M, Chen L, Zhang L, He P, Villalobos A, McCarthy TJ, Halldin C, Varrone A. Arakawa R, et al. Eur J Nucl Med Mol Imaging. 2020 Sep;47(10):2429-2439. doi: 10.1007/s00259-020-04739-5. Epub 2020 Mar 6. Eur J Nucl Med Mol Imaging. 2020. PMID: 32140803 Free PMC article.
First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B.
Wakabayashi Y, Stenkrona P, Arakawa R, Yan X, Van Buskirk MG, Jenkins MD, Santamaria JAM, Maresca KP, Takano A, Liow JS, Chappie TA, Varrone A, Nag S, Zhang L, Hughes ZA, Schmidt CJ, Doran SD, Mannes A, Zanotti-Fregonara P, Ooms M, Morse CL, Zoghbi SS, Halldin C, Pike VW, Innis RB. Wakabayashi Y, et al. Among authors: arakawa r. J Nucl Med. 2022 Dec;63(12):1919-1924. doi: 10.2967/jnumed.122.263838. Epub 2022 Jun 30. J Nucl Med. 2022. PMID: 35772961 Free PMC article.
298 results