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Conjugation of Triterpenic Acids of Ursane and Oleanane Types with Mitochondria-Targeting Cation F16 Synergistically Enhanced Their Cytotoxicity against Tumor Cells.
Membranes (Basel). 2023 May 30;13(6):563. doi: 10.3390/membranes13060563.
Membranes (Basel). 2023.
PMID: 37367767
Free PMC article.
Comparative Study of Cytotoxic and Membranotropic Properties of Betulinic Acid-F16 Conjugate on Breast Adenocarcinoma Cells (MCF-7) and Primary Human Fibroblasts.
Belosludtsev KN, Ilzorkina AI, Belosludtseva NV, Sharapov VA, Penkov NV, Serov DA, Karagyaur MN, Nedopekina DA, Davletshin EV, Solovieva ME, Spivak AY, Kuzmina US, Vakhitova YV, Akatov VS, Dubinin MV.
Belosludtsev KN, et al. Among authors: davletshin ev.
Biomedicines. 2022 Nov 11;10(11):2903. doi: 10.3390/biomedicines10112903.
Biomedicines. 2022.
PMID: 36428470
Free PMC article.
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Effect of F16-Betulin Conjugate on Mitochondrial Membranes and Its Role in Cell Death Initiation.
Dubinin MV, Semenova AA, Nedopekina DA, Davletshin EV, Spivak AY, Belosludtsev KN.
Dubinin MV, et al. Among authors: davletshin ev.
Membranes (Basel). 2021 May 10;11(5):352. doi: 10.3390/membranes11050352.
Membranes (Basel). 2021.
PMID: 34068772
Free PMC article.
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Mitochondria-targeted prooxidant effects of betulinic acid conjugated with delocalized lipophilic cation F16.
Dubinin MV, Semenova AA, Ilzorkina AI, Penkov NV, Nedopekina DA, Sharapov VA, Khoroshavina EI, Davletshin EV, Belosludtseva NV, Spivak AY, Belosludtsev KN.
Dubinin MV, et al. Among authors: davletshin ev.
Free Radic Biol Med. 2021 May 20;168:55-69. doi: 10.1016/j.freeradbiomed.2021.03.036. Epub 2021 Apr 1.
Free Radic Biol Med. 2021.
PMID: 33812008
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