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Trans-sialidase-based vaccine candidate protects against Trypanosoma cruzi infection, not only inducing an effector immune response but also affecting cells with regulatory/suppressor phenotype.
Prochetto E, Roldán C, Bontempi IA, Bertona D, Peverengo L, Vicco MH, Rodeles LM, Pérez AR, Marcipar IS, Cabrera G. Prochetto E, et al. Oncotarget. 2017 May 25;8(35):58003-58020. doi: 10.18632/oncotarget.18217. eCollection 2017 Aug 29. Oncotarget. 2017. PMID: 28938533 Free PMC article.
Genetic Engineering of Lactococcus lactis Co-producing Antigen and the Mucosal Adjuvant 3' 5'- cyclic di Adenosine Monophosphate (c-di-AMP) as a Design Strategy to Develop a Mucosal Vaccine Prototype.
Quintana I, Espariz M, Villar SR, González FB, Pacini MF, Cabrera G, Bontempi I, Prochetto E, Stülke J, Perez AR, Marcipar I, Blancato V, Magni C. Quintana I, et al. Among authors: marcipar i. Front Microbiol. 2018 Sep 4;9:2100. doi: 10.3389/fmicb.2018.02100. eCollection 2018. Front Microbiol. 2018. PMID: 30258417 Free PMC article.
Intranasal trans-sialidase-based vaccine against Trypanosoma cruzi triggers a mixed cytokine profile in the nasopharynx-associated lymphoid tissue and confers local and systemic immunogenicity.
Pacini MF, Balbi CB, Dinatale B, González FB, Prochetto E, De Hernández MA, Cribb P, Farré C, Espariz M, Blancato VS, Magni C, Marcipar I, Pérez AR. Pacini MF, et al. Among authors: marcipar i. Acta Trop. 2023 May;241:106889. doi: 10.1016/j.actatropica.2023.106889. Epub 2023 Mar 7. Acta Trop. 2023. PMID: 36893830
74 results