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Evaluation of the microbiota-sparing properties of the anti-staphylococcal antibiotic afabicin.
Nowakowska J, Cameron DR, De Martino A, Kühn J, Le Fresne-Languille S, Leuillet S, Amouzou Y, Wittke F, Carton T, Le Vacon F, Chaves RL, Nicolas-Metral V, Vuagniaux G. Nowakowska J, et al. Among authors: vuagniaux g. J Antimicrob Chemother. 2023 Aug 2;78(8):1900-1908. doi: 10.1093/jac/dkad181. J Antimicrob Chemother. 2023. PMID: 37294305 Free PMC article.
Exploratory window-of-opportunity trial to investigate the tumor pharmacokinetics/pharmacodynamics of the IAP antagonist Debio 1143 in patients with head and neck cancer.
Gomez-Roca C, Even C, Le Tourneau C, Basté N, Delord JP, Sarini J, Vergez S, Temam S, Hoffmann C, Rochaix P, Borcoman E, Gavillet B, Rouits E, Ménétrey A, Brichory F, Purcea D, Vuagniaux G, Zanna C. Gomez-Roca C, et al. Among authors: vuagniaux g. Clin Transl Sci. 2022 Jan;15(1):55-62. doi: 10.1111/cts.13002. Epub 2021 Nov 11. Clin Transl Sci. 2022. PMID: 33742767 Free PMC article.
Phase I Trial of Debio 1143, an Antagonist of Inhibitor of Apoptosis Proteins, Combined with Cisplatin Chemoradiotherapy in Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck.
Le Tourneau C, Tao Y, Gomez-Roca C, Cristina V, Borcoman E, Deutsch E, Bahleda R, Calugaru V, Modesto A, Rouits E, Gollmer K, Vuagniaux G, Crompton P, Zanna C, Szyldergemajn S, Delord JP, Bourhis J. Le Tourneau C, et al. Among authors: vuagniaux g. Clin Cancer Res. 2020 Dec 15;26(24):6429-6436. doi: 10.1158/1078-0432.CCR-20-0425. Epub 2020 Sep 29. Clin Cancer Res. 2020. PMID: 32994295 Clinical Trial.
Nuclear Imaging Study of the Pharmacodynamic Effects of Debio 1143, an Antagonist of Multiple Inhibitor of Apoptosis Proteins (IAPs), in a Triple-Negative Breast Cancer Model.
Bellaye PS, Oudot A, Vrigneaud JM, Raguin O, Bichat F, Vaslin A, Maby-El Hajjami H, Zanna C, Vuagniaux G, Fumoleau P, Denat F, Brunotte F, Collin B. Bellaye PS, et al. Among authors: vuagniaux g. Contrast Media Mol Imaging. 2018 Dec 2;2018:8494031. doi: 10.1155/2018/8494031. eCollection 2018. Contrast Media Mol Imaging. 2018. PMID: 30627061 Free PMC article.
A Pathogen-Selective Antibiotic Minimizes Disturbance to the Microbiome.
Yao J, Carter RA, Vuagniaux G, Barbier M, Rosch JW, Rock CO. Yao J, et al. Among authors: vuagniaux g. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4264-73. doi: 10.1128/AAC.00535-16. Print 2016 Jul. Antimicrob Agents Chemother. 2016. PMID: 27161626 Free PMC article.
41 results