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TMPRSS2 Inhibitor Discovery Facilitated through an In Silico and Biochemical Screening Platform.
ACS Med Chem Lett. 2023 May 30;14(6):860-866. doi: 10.1021/acsmedchemlett.3c00035. eCollection 2023 Jun 8.
ACS Med Chem Lett. 2023.
PMID: 37284689
Free article.
Norstictic Acid Is a Selective Allosteric Transcriptional Regulator.
Garlick JM, Sturlis SM, Bruno PA, Yates JA, Peiffer AL, Liu Y, Goo L, Bao L, De Salle SN, Tamayo-Castillo G, Brooks CL 3rd, Merajver SD, Mapp AK.
Garlick JM, et al. Among authors: peiffer al.
J Am Chem Soc. 2021 Jun 30;143(25):9297-9302. doi: 10.1021/jacs.1c03258. Epub 2021 Jun 17.
J Am Chem Soc. 2021.
PMID: 34137598
Free PMC article.
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Allostery in the dynamic coactivator domain KIX occurs through minor conformational micro-states.
Peiffer AL, Garlick JM, Joy ST, Mapp AK, Brooks CL 3rd.
Peiffer AL, et al.
PLoS Comput Biol. 2022 Apr 22;18(4):e1009977. doi: 10.1371/journal.pcbi.1009977. eCollection 2022 Apr.
PLoS Comput Biol. 2022.
PMID: 35452454
Free PMC article.
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Conservation of coactivator engagement mechanism enables small-molecule allosteric modulators.
Henderson AR, Henley MJ, Foster NJ, Peiffer AL, Beyersdorf MS, Stanford KD, Sturlis SM, Linhares BM, Hill ZB, Wells JA, Cierpicki T, Brooks CL 3rd, Fierke CA, Mapp AK.
Henderson AR, et al. Among authors: peiffer al.
Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):8960-8965. doi: 10.1073/pnas.1806202115. Epub 2018 Aug 20.
Proc Natl Acad Sci U S A. 2018.
PMID: 30127017
Free PMC article.
Item in Clipboard
Soluble Human Lectins at the Host-Microbe Interface.
Peiffer AL, Dugan AE, Kiessling LL.
Peiffer AL, et al.
Annu Rev Biochem. 2024 Apr 19. doi: 10.1146/annurev-biochem-062917-012322. Online ahead of print.
Annu Rev Biochem. 2024.
PMID: 38640018
Review.
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Advances in glycoscience to understand viral infection and colonization.
Dugan AE, Peiffer AL, Kiessling LL.
Dugan AE, et al. Among authors: peiffer al.
Nat Methods. 2022 Apr;19(4):384-387. doi: 10.1038/s41592-022-01451-0.
Nat Methods. 2022.
PMID: 35396476
No abstract available.
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TMPRSS2 inhibitor discovery facilitated through an in silico and biochemical screening platform.
Peiffer AL, Garlick JM, Wu Y, Soellner MB, Brooks CL 3rd, Mapp AK.
Peiffer AL, et al.
bioRxiv [Preprint]. 2021 Mar 27:2021.03.22.436465. doi: 10.1101/2021.03.22.436465.
bioRxiv. 2021.
PMID: 33791707
Free PMC article.
Updated.
Preprint.
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