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Phosphorylation of α-synuclein at T64 results in distinct oligomers and exerts toxicity in models of Parkinson's disease.
Matsui H, Ito S, Matsui H, Ito J, Gabdulkhaev R, Hirose M, Yamanaka T, Koyama A, Kato T, Tanaka M, Uemura N, Matsui N, Hirokawa S, Yoshihama M, Shimozawa A, Kubo SI, Iwasaki K, Hasegawa M, Takahashi R, Hirai K, Kakita A, Onodera O. Matsui H, et al. Among authors: koyama a. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2214652120. doi: 10.1073/pnas.2214652120. Epub 2023 May 30. Proc Natl Acad Sci U S A. 2023. PMID: 37252975 Free PMC article.
TDP-43 mutation in familial amyotrophic lateral sclerosis.
Yokoseki A, Shiga A, Tan CF, Tagawa A, Kaneko H, Koyama A, Eguchi H, Tsujino A, Ikeuchi T, Kakita A, Okamoto K, Nishizawa M, Takahashi H, Onodera O. Yokoseki A, et al. Among authors: koyama a. Ann Neurol. 2008 Apr;63(4):538-42. doi: 10.1002/ana.21392. Ann Neurol. 2008. PMID: 18438952
Haploinsufficiency of CSF-1R and clinicopathologic characterization in patients with HDLS.
Konno T, Tada M, Tada M, Koyama A, Nozaki H, Harigaya Y, Nishimiya J, Matsunaga A, Yoshikura N, Ishihara K, Arakawa M, Isami A, Okazaki K, Yokoo H, Itoh K, Yoneda M, Kawamura M, Inuzuka T, Takahashi H, Nishizawa M, Onodera O, Kakita A, Ikeuchi T. Konno T, et al. Among authors: koyama a. Neurology. 2014 Jan 14;82(2):139-48. doi: 10.1212/WNL.0000000000000046. Epub 2013 Dec 13. Neurology. 2014. PMID: 24336230 Free PMC article.
Distinct molecular mechanisms of HTRA1 mutants in manifesting heterozygotes with CARASIL.
Nozaki H, Kato T, Nihonmatsu M, Saito Y, Mizuta I, Noda T, Koike R, Miyazaki K, Kaito M, Ito S, Makino M, Koyama A, Shiga A, Uemura M, Sekine Y, Murakami A, Moritani S, Hara K, Yokoseki A, Kuwano R, Endo N, Momotsu T, Yoshida M, Nishizawa M, Mizuno T, Onodera O. Nozaki H, et al. Among authors: koyama a. Neurology. 2016 May 24;86(21):1964-74. doi: 10.1212/WNL.0000000000002694. Epub 2016 Apr 27. Neurology. 2016. PMID: 27164673
Increased cytoplasmic TARDBP mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43.
Koyama A, Sugai A, Kato T, Ishihara T, Shiga A, Toyoshima Y, Koyama M, Konno T, Hirokawa S, Yokoseki A, Nishizawa M, Kakita A, Takahashi H, Onodera O. Koyama A, et al. Among authors: koyama m. Nucleic Acids Res. 2016 Jul 8;44(12):5820-36. doi: 10.1093/nar/gkw499. Epub 2016 Jun 2. Nucleic Acids Res. 2016. PMID: 27257061 Free PMC article.
764 results