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Biallelic NFATC1 mutations cause an inborn error of immunity with impaired CD8+ T-cell function and perturbed glycolysis.
Kostel Bal S, Giuliani S, Block J, Repiscak P, Hafemeister C, Shahin T, Kasap N, Ransmayr B, Miao Y, van de Wetering C, Frohne A, Jimenez Heredia R, Schuster M, Zoghi S, Hertlein V, Thian M, Bykov A, Babayeva R, Bilgic Eltan S, Karakoc-Aydiner E, Shaw LE, Chowdhury I, Varjosalo M, Argüello RJ, Farlik M, Ozen A, Serfling E, Dupré L, Bock C, Halbritter F, Hannich JT, Castanon I, Kraakman MJ, Baris S, Boztug K. Kostel Bal S, et al. Among authors: serfling e. Blood. 2023 Aug 31;142(9):827-845. doi: 10.1182/blood.2022018303. Blood. 2023. PMID: 37249233
NFATc1 induction by an intronic enhancer restricts NKT γδ cell formation.
Giampaolo S, Chiarolla CM, Knöpper K, Vaeth M, Klein M, Muhammad A, Bopp T, Berberich-Siebelt F, Patra AK, Serfling E, Klein-Hessling S. Giampaolo S, et al. Among authors: serfling e. iScience. 2023 Feb 19;26(3):106234. doi: 10.1016/j.isci.2023.106234. eCollection 2023 Mar 17. iScience. 2023. PMID: 36926655 Free PMC article.
NFAT5 Controls the Integrity of Epidermis.
Muhammad K, Xavier D, Klein-Hessling S, Azeem M, Rauschenberger T, Murti K, Avots A, Goebeler M, Klein M, Bopp T, Sielaff M, Tenzer S, Möckel S, Aramburu J, López-Rodríguez C, Kerstan A, Serfling E. Muhammad K, et al. Among authors: serfling e. Front Immunol. 2021 Dec 9;12:780727. doi: 10.3389/fimmu.2021.780727. eCollection 2021. Front Immunol. 2021. PMID: 34956208 Free PMC article.
Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivity.
Xiao Y, Qureischi M, Dietz L, Vaeth M, Vallabhapurapu SD, Klein-Hessling S, Klein M, Liang C, König A, Serfling E, Mottok A, Bopp T, Rosenwald A, Buttmann M, Berberich I, Beilhack A, Berberich-Siebelt F. Xiao Y, et al. Among authors: serfling e. J Exp Med. 2021 Jan 4;218(1):e20181853. doi: 10.1084/jem.20181853. J Exp Med. 2021. PMID: 32986812 Free PMC article.
Current Developments in the Immunology of Psoriasis.
Grän F, Kerstan A, Serfling E, Goebeler M, Muhammad K. Grän F, et al. Among authors: serfling e. Yale J Biol Med. 2020 Mar 27;93(1):97-110. eCollection 2020 Mar. Yale J Biol Med. 2020. PMID: 32226340 Free PMC article. Review.
142 results