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In vitro evaluation of antileishmanial activity, mode of action and cellular response induced by vanillin synthetic derivatives against Leishmania species able to cause cutaneous and visceral leishmaniasis.
Freitas CS, Santiago SS, Lage DP, Antinarelli LMR, Oliveira FM, Vale DL, Martins VT, Magalhaes LND, Bandeira RS, Ramos FF, Pereira IAG, de Jesus MM, Ludolf F, Tavares GSV, Costa AV, Ferreira RS, Coimbra ES, Teixeira RR, Coelho EAF. Freitas CS, et al. Among authors: antinarelli lmr. Exp Parasitol. 2023 Aug;251:108555. doi: 10.1016/j.exppara.2023.108555. Epub 2023 May 27. Exp Parasitol. 2023. PMID: 37247802
A Pluronic® F127-based polymeric micelle system containing an antileishmanial molecule is immunotherapeutic and effective in the treatment against Leishmania amazonensis infection.
Tavares GSV, Mendonça DVC, Miyazaki CK, Lage DP, Soyer TG, Carvalho LM, Ottoni FM, Dias DS, Ribeiro PAF, Antinarelli LMR, Ludolf F, Duarte MC, Coimbra ES, Chávez-Fumagalli MA, Roatt BM, Menezes-Souza D, Barichello JM, Alves RJ, Coelho EAF. Tavares GSV, et al. Among authors: antinarelli lmr. Parasitol Int. 2019 Feb;68(1):63-72. doi: 10.1016/j.parint.2018.10.005. Epub 2018 Oct 16. Parasitol Int. 2019. PMID: 30339837
Evaluation of the in vitro and in vivo antileishmanial activity of a chloroquinolin derivative against Leishmania species capable of causing tegumentary and visceral leishmaniasis.
Soyer TG, Mendonça DVC, Tavares GSV, Lage DP, Dias DS, Ribeiro PAF, Perin L, Ludolf F, Coelho VTS, Ferreira ACG, Neves PHAS, Matos GF, Chávez-Fumagalli MA, Coimbra ES, Pereira GR, Coelho EAF, Antinarelli LMR. Soyer TG, et al. Among authors: antinarelli lmr. Exp Parasitol. 2019 Apr;199:30-37. doi: 10.1016/j.exppara.2019.02.019. Epub 2019 Feb 25. Exp Parasitol. 2019. PMID: 30817917
A chloroquinoline derivate presents effective in vitro and in vivo antileishmanial activity against Leishmania species that cause tegumentary and visceral leishmaniasis.
Sousa JKT, Antinarelli LMR, Mendonça DVC, Lage DP, Tavares GSV, Dias DS, Ribeiro PAF, Ludolf F, Coelho VTS, Oliveira-da-Silva JA, Perin L, Oliveira BA, Alvarenga DF, Chávez-Fumagalli MA, Brandão GC, Nobre V, Pereira GR, Coimbra ES, Coelho EAF. Sousa JKT, et al. Among authors: antinarelli lmr. Parasitol Int. 2019 Dec;73:101966. doi: 10.1016/j.parint.2019.101966. Epub 2019 Jul 27. Parasitol Int. 2019. PMID: 31362122
Digitoxigenin presents an effective and selective antileishmanial action against Leishmania infantum and is a potential therapeutic agent for visceral leishmaniasis.
Freitas CS, Oliveira-da-Silva JA, Lage DP, Costa RR, Mendonça DVC, Martins VT, Reis TAR, Antinarelli LMR, Machado AS, Tavares GSV, Ramos FF, Coelho VTS, Brito RCF, Ludolf F, Chávez-Fumagalli MA, Roatt BM, Ramos GS, Munkert J, Ottoni FM, Campana PRV, Humbert MV, Coimbra ES, Braga FC, Pádua RM, Coelho EAF. Freitas CS, et al. Among authors: antinarelli lmr. Parasitol Res. 2021 Jan;120(1):321-335. doi: 10.1007/s00436-020-06971-2. Epub 2020 Nov 16. Parasitol Res. 2021. PMID: 33191446 Free PMC article.
Ivermectin presents effective and selective antileishmanial activity in vitro and in vivo against Leishmania infantum and is therapeutic against visceral leishmaniasis.
Reis TAR, Oliveira-da-Silva JA, Tavares GSV, Mendonça DVC, Freitas CS, Costa RR, Lage DP, Martins VT, Machado AS, Ramos FF, Silva AM, Ludolf F, Antinarelli LMR, Brito RCF, Chávez-Fumagalli MA, Humbert MV, Roatt BM, Coimbra ES, Coelho EAF. Reis TAR, et al. Among authors: antinarelli lmr. Exp Parasitol. 2021 Feb;221:108059. doi: 10.1016/j.exppara.2020.108059. Epub 2020 Dec 16. Exp Parasitol. 2021. PMID: 33338468
Acarbose presents in vitro and in vivo antileishmanial activity against Leishmania infantum and is a promising therapeutic candidate against visceral leishmaniasis.
Costa RR, Oliveira-da-Silva JA, Reis TAR, Tavares GSV, Mendonça DVC, Freitas CS, Lage DP, Martins VT, Antinarelli LMR, Machado AS, Bandeira RS, Ludolf F, Santos TTO, Brito RCF, Humbert MV, Menezes-Souza D, Duarte MC, Chávez-Fumagalli MA, Roatt BM, Coimbra ES, Coelho EAF. Costa RR, et al. Among authors: antinarelli lmr. Med Microbiol Immunol. 2021 Jun;210(2-3):133-147. doi: 10.1007/s00430-021-00707-4. Epub 2021 Apr 18. Med Microbiol Immunol. 2021. PMID: 33870453 Free PMC article.
In vivo antileishmanial efficacy of a naphthoquinone derivate incorporated into a Pluronic® F127-based polymeric micelle system against Leishmania amazonensis infection.
Mendonça DVC, Tavares GSV, Lage DP, Soyer TG, Carvalho LM, Dias DS, Ribeiro PAF, Ottoni FM, Antinarelli LMR, Vale DL, Ludolf F, Duarte MC, Coimbra ES, Chávez-Fumagalli MA, Roatt BM, Menezes-Souza D, Barichello JM, Alves RJ, Coelho EAF. Mendonça DVC, et al. Among authors: antinarelli lmr. Biomed Pharmacother. 2019 Jan;109:779-787. doi: 10.1016/j.biopha.2018.10.143. Epub 2018 Nov 5. Biomed Pharmacother. 2019. PMID: 30551531 Free article.
34 results