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Targeting the NLRP3 inflammasome reduces inflammation in hidradenitis suppurativa skin.
Moran B, Smith CM, Zaborowski A, Ryan M, Karman J, Dunstan RW, Smith KM, Hambly R, Musilova J, Petrasca A, Fabre A, O'Donnell M, Hokamp K, Mills KHG, Housley WJ, Winter DC, Kirby B, Fletcher JM. Moran B, et al. Among authors: dunstan rw. Br J Dermatol. 2023 Sep 15;189(4):447-458. doi: 10.1093/bjd/ljad184. Br J Dermatol. 2023. PMID: 37243544
Cytokine induced 3-D organotypic psoriasis skin model demonstrates distinct roles for NF-κB and JAK pathways in disease pathophysiology.
Todorović V, McDonald HA, Hoover P, Wetter JB, Marinopoulos AE, Woody CL, Miller L, Finkielsztein A, Dunstan RW, Paller AS, Honore P, Getsios S, Scott VE. Todorović V, et al. Among authors: dunstan rw. Exp Dermatol. 2022 Jul;31(7):1036-1047. doi: 10.1111/exd.14551. Epub 2022 Mar 7. Exp Dermatol. 2022. PMID: 35213752 Free PMC article.
Pristane-Accelerated Autoimmune Disease in (SWR X NZB) F1 Mice Leads to Prominent Tubulointerstitial Inflammation and Human Lupus Nephritis-Like Fibrosis.
Gardet A, Chou WC, Reynolds TL, Velez DB, Fu K, Czerkowicz JM, Bajko J, Ranger AM, Allaire N, Kerns HM, Ryan S, Legault HM, Dunstan RW, Lafyatis R, Lukashev M, Viney JL, Browning JL, Rabah D. Gardet A, et al. Among authors: dunstan rw. PLoS One. 2016 Oct 19;11(10):e0164423. doi: 10.1371/journal.pone.0164423. eCollection 2016. PLoS One. 2016. PMID: 27760209 Free PMC article.
JC Polyomavirus Abundance and Distribution in Progressive Multifocal Leukoencephalopathy (PML) Brain Tissue Implicates Myelin Sheath in Intracerebral Dissemination of Infection.
Wharton KA Jr, Quigley C, Themeles M, Dunstan RW, Doyle K, Cahir-McFarland E, Wei J, Buko A, Reid CE, Sun C, Carmillo P, Sur G, Carulli JP, Mansfield KG, Westmoreland SV, Staugaitis SM, Fox RJ, Meier W, Goelz SE. Wharton KA Jr, et al. Among authors: dunstan rw. PLoS One. 2016 May 18;11(5):e0155897. doi: 10.1371/journal.pone.0155897. eCollection 2016. PLoS One. 2016. PMID: 27191595 Free PMC article.
BIIB042, a novel γ-secretase modulator, reduces amyloidogenic Aβ isoforms in primates and rodents and plaque pathology in a mouse model of Alzheimer's disease.
Scannevin RH, Chollate S, Brennan MS, Snodgrass-Belt PA, Peng H, Xu L, Jung MY, Bussiere T, Arastu MF, Talreja T, Xin Z, Dunstan RW, Fahrer D, Rohde E, Dunah AW, Wang J, Kumaravel G, Taveras AG, Moore Arnold H, Rhodes KJ. Scannevin RH, et al. Among authors: dunstan rw. Neuropharmacology. 2016 Apr;103:57-68. doi: 10.1016/j.neuropharm.2015.12.006. Epub 2015 Dec 12. Neuropharmacology. 2016. PMID: 26690893
77 results