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LOXL4, but not LOXL2, is the critical determinant of pathological collagen cross-linking and fibrosis in the lung.
Ma HY, Li Q, Wong WR, N'Diaye EN, Caplazi P, Bender H, Huang Z, Arlantico A, Jeet S, Wong A, Emson C, Brightbill H, Tam L, Newman R, Roose-Girma M, Sandoval W, Ding N. Ma HY, et al. Among authors: wong a, wong wr. Sci Adv. 2023 May 26;9(21):eadf0133. doi: 10.1126/sciadv.adf0133. Epub 2023 May 26. Sci Adv. 2023. PMID: 37235663 Free PMC article.
BMP1 is not required for lung fibrosis in mice.
Ma HY, N'Diaye EN, Caplazi P, Huang Z, Arlantico A, Jeet S, Wong A, Brightbill HD, Li Q, Wong WR, Sandoval W, Tam L, Newman R, Roose-Girma M, Ding N. Ma HY, et al. Among authors: wong a, wong wr. Sci Rep. 2022 Mar 31;12(1):5466. doi: 10.1038/s41598-022-09557-3. Sci Rep. 2022. PMID: 35361882 Free PMC article.
A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis.
Xi Y, LaCanna R, Ma HY, N'Diaye EN, Gierke S, Caplazi P, Sagolla M, Huang Z, Lucio L, Arlantico A, Jeet S, Brightbill H, Emson C, Wong A, Morshead KB, DePianto DJ, Roose-Girma M, Yu C, Tam L, Jia G, Ramalingam TR, Marsters S, Ashkenazi A, Kim SH, Kelly R, Wu S, Wolters PJ, Feldstein AE, Vander Heiden JA, Ding N. Xi Y, et al. Among authors: wong a. Cell Metab. 2022 Sep 6;34(9):1377-1393.e8. doi: 10.1016/j.cmet.2022.07.009. Epub 2022 Aug 19. Cell Metab. 2022. PMID: 35987202 Free article.
Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling.
Samie M, Lim J, Verschueren E, Baughman JM, Peng I, Wong A, Kwon Y, Senbabaoglu Y, Hackney JA, Keir M, Mckenzie B, Kirkpatrick DS, van Lookeren Campagne M, Murthy A. Samie M, et al. Among authors: wong a. Nat Immunol. 2018 Mar;19(3):246-254. doi: 10.1038/s41590-017-0042-6. Epub 2018 Jan 22. Nat Immunol. 2018. PMID: 29358708
7,378 results