Freeman ADJ - Search Results

1

Biochemical and mechanistic analysis of the cleavage of branched DNA by human ANKLE1.

Freeman ADJ, Déclais AC, Wilson TJ, Lilley DMJ. Freeman ADJ, et al. Nucleic Acids Res. 2023 Jun 23;51(11):5743-5754. doi: 10.1093/nar/gkad416. Nucleic Acids Res. 2023. PMID: 37216589 Free PMC article.

2

A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1.

Liu Y, Freeman AD, Déclais AC, Lilley DMJ. Liu Y, et al. Nucleic Acids Res. 2018 Nov 16;46(20):11089-11098. doi: 10.1093/nar/gky863. Nucleic Acids Res. 2018. PMID: 30247722 Free PMC article.

3

Human ANKLE1 Is a Nuclease Specific for Branched DNA.

Song J, Freeman ADJ, Knebel A, Gartner A, Lilley DMJ. Song J, et al. Among authors: freeman adj. J Mol Biol. 2020 Oct 2;432(21):5825-5834. doi: 10.1016/j.jmb.2020.08.022. Epub 2020 Aug 28. J Mol Biol. 2020. PMID: 32866453 Free PMC article.

4

The complex between a four-way DNA junction and T7 endonuclease I.

Déclais AC, Fogg JM, Freeman AD, Coste F, Hadden JM, Phillips SE, Lilley DM. Déclais AC, et al. EMBO J. 2003 Mar 17;22(6):1398-409. doi: 10.1093/emboj/cdg132. EMBO J. 2003. PMID: 12628932 Free PMC article.

5

Metal ion binding in the active site of the junction-resolving enzyme T7 endonuclease I in the presence and in the absence of DNA.

Freeman AD, Déclais AC, Lilley DM. Freeman AD, et al. J Mol Biol. 2003 Oct 10;333(1):59-73. doi: 10.1016/j.jmb.2003.08.010. J Mol Biol. 2003. PMID: 14516743

6

Structural recognition between a four-way DNA junction and a resolving enzyme.

Déclais AC, Liu J, Freeman AD, Lilley DM. Déclais AC, et al. J Mol Biol. 2006 Jun 23;359(5):1261-76. doi: 10.1016/j.jmb.2006.04.037. Epub 2006 May 2. J Mol Biol. 2006. PMID: 16690083

7

The importance of the N-terminus of T7 endonuclease I in the interaction with DNA junctions.

Freeman AD, Déclais AC, Lilley DM. Freeman AD, et al. J Mol Biol. 2013 Jan 23;425(2):395-410. doi: 10.1016/j.jmb.2012.11.029. Epub 2012 Dec 1. J Mol Biol. 2013. PMID: 23207296

8

GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes.

Freeman ADJ, Liu Y, Déclais AC, Gartner A, Lilley DMJ. Freeman ADJ, et al. J Mol Biol. 2014 Dec 12;426(24):3946-3959. doi: 10.1016/j.jmb.2014.10.008. Epub 2014 Oct 12. J Mol Biol. 2014. PMID: 25315822 Free PMC article.

9

Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.

Liu Y, Freeman ADJ, Déclais AC, Wilson TJ, Gartner A, Lilley DMJ. Liu Y, et al. Among authors: freeman adj. Cell Rep. 2015 Dec 22;13(11):2565-2575. doi: 10.1016/j.celrep.2015.11.042. Epub 2015 Dec 10. Cell Rep. 2015. PMID: 26686639 Free PMC article.

10

Analysis of the Intrinsically Disordered N-Terminus of the DNA Junction-Resolving Enzyme T7 Endonuclease I: Identification of Structure Formed upon DNA Binding.

Freeman AD, Stevens M, Declais AC, Leahy A, Mackay K, El Mkami H, Lilley DM, Norman DG. Freeman AD, et al. Biochemistry. 2016 Aug 2;55(30):4166-72. doi: 10.1021/acs.biochem.6b00242. Epub 2016 Jul 18. Biochemistry. 2016. PMID: 27387136 Free PMC article.

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