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Deficiency of germinal center kinase TRAF2 and NCK-interacting kinase (TNIK) in B cells does not affect atherosclerosis.
van Os BW, Kusters PJH, den Toom M, Beckers L, van Tiel CM, Vos WG, de Jong E, Kieser A, van Roomen C, Binder CJ, Reiche ME, de Winther MP, Bosmans LA, Lutgens E. van Os BW, et al. Among authors: kusters pjh. Front Cardiovasc Med. 2023 May 5;10:1171764. doi: 10.3389/fcvm.2023.1171764. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37215541 Free PMC article.
Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis.
Aarts SA, Seijkens TT, Kusters PJ, van Tiel CM, Reiche ME, den Toom M, Beckers L, van Roomen CP, de Winther MP, Kooij G, Lutgens E. Aarts SA, et al. J Pathol. 2019 Apr;247(4):471-480. doi: 10.1002/path.5205. Epub 2019 Jan 30. J Pathol. 2019. PMID: 30471110 Free PMC article.
The CD40-CD40L Dyad as Immunotherapeutic Target in Cardiovascular Disease.
Bosmans LA, Bosch L, Kusters PJH, Lutgens E, Seijkens TTP. Bosmans LA, et al. Among authors: kusters pjh. J Cardiovasc Transl Res. 2021 Feb;14(1):13-22. doi: 10.1007/s12265-020-09994-3. Epub 2020 Mar 28. J Cardiovasc Transl Res. 2021. PMID: 32222950 Free PMC article. Review.
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.
Seijkens TTP, van Tiel CM, Kusters PJH, Atzler D, Soehnlein O, Zarzycka B, Aarts SABM, Lameijer M, Gijbels MJ, Beckers L, den Toom M, Slütter B, Kuiper J, Duchene J, Aslani M, Megens RTA, van 't Veer C, Kooij G, Schrijver R, Hoeksema MA, Boon L, Fay F, Tang J, Baxter S, Jongejan A, Moerland PD, Vriend G, Bleijlevens B, Fisher EA, Duivenvoorden R, Gerdes N, de Winther MPJ, Nicolaes GA, Mulder WJM, Weber C, Lutgens E. Seijkens TTP, et al. Among authors: kusters pjh. J Am Coll Cardiol. 2018 Feb 6;71(5):527-542. doi: 10.1016/j.jacc.2017.11.055. J Am Coll Cardiol. 2018. PMID: 29406859 Free PMC article.
Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death.
Seijkens TTP, Poels K, Meiler S, van Tiel CM, Kusters PJH, Reiche M, Atzler D, Winkels H, Tjwa M, Poelman H, Slütter B, Kuiper J, Gijbels M, Kuivenhoven JA, Matic LP, Paulsson-Berne G, Hedin U, Hansson GK, Nicolaes GAF, Daemen MJAP, Weber C, Gerdes N, de Winther MPJ, Lutgens E. Seijkens TTP, et al. Among authors: kusters pjh. Eur Heart J. 2019 Jan 21;40(4):372-382. doi: 10.1093/eurheartj/ehy714. Eur Heart J. 2019. PMID: 30452556 Free PMC article.
Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans.
Shami A, Atzler D, Bosmans LA, Winkels H, Meiler S, Lacy M, van Tiel C, Ta Megens R, Nitz K, Baardman J, Kusters P, Seijkens T, Buerger C, Janjic A, Riccardi C, Edsfeldt A, Monaco C, Daemen M, de Winther MPJ, Nilsson J, Weber C, Gerdes N, Gonçalves I, Lutgens E. Shami A, et al. Eur Heart J. 2020 Aug 14;41(31):2938-2948. doi: 10.1093/eurheartj/ehaa484. Eur Heart J. 2020. PMID: 32728688 Free PMC article.
Immune Checkpoint Inhibitor Therapy Aggravates T Cell-Driven Plaque Inflammation in Atherosclerosis.
Poels K, van Leent MMT, Boutros C, Tissot H, Roy S, Meerwaldt AE, Toner YCA, Reiche ME, Kusters PJH, Malinova T, Huveneers S, Kaufman AE, Mani V, Fayad ZA, de Winther MPJ, Marabelle A, Mulder WJM, Robert C, Seijkens TTP, Lutgens E. Poels K, et al. Among authors: kusters pjh. JACC CardioOncol. 2020 Oct 6;2(4):599-610. doi: 10.1016/j.jaccao.2020.08.007. eCollection 2020 Nov. JACC CardioOncol. 2020. PMID: 34396271 Free PMC article.
24 results