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Improving combination therapies: targeting A2B-adenosine receptor to modulate metabolic tumor microenvironment and immunosuppression.
Evans JV, Suman S, Goruganthu MUL, Tchekneva EE, Guan S, Arasada RR, Antonucci A, Piao L, Ilgisonis I, Bobko AA, Driesschaert B, Uzhachenko RV, Hoyd R, Samouilov A, Amann J, Wu R, Wei L, Pallerla A, Ryzhov SV, Feoktistov I, Park KP, Kikuchi T, Castro J, Ivanova AV, Kanagasabai T, Owen DH, Spakowicz DJ, Zweier JL, Carbone DP, Novitskiy SV, Khramtsov VV, Shanker A, Dikov MM. Evans JV, et al. Among authors: spakowicz dj. J Natl Cancer Inst. 2023 Nov 8;115(11):1404-1419. doi: 10.1093/jnci/djad091. J Natl Cancer Inst. 2023. PMID: 37195421 Free PMC article.
Mean platelet volume, thrombocytosis, and survival in non-small cell lung cancer patients treated with first-line pembrolizumab alone or with chemotherapy.
Li M, Zhao S, Lopez G, Secor A, Das P, Surya N, Grogan M, Patel S, Chakravarthy K, Miah A, Spakowicz D, Tinoco G, Li Z, Wei L, He K, Bertino E, Alahmadi A, Memmott R, Kaufman J, Shields PG, Carbone DP, Presley CJ, Otterson GA, Owen DH. Li M, et al. Cancer Immunol Immunother. 2023 Jul;72(7):2067-2074. doi: 10.1007/s00262-023-03392-9. Epub 2023 Feb 16. Cancer Immunol Immunother. 2023. PMID: 36795122 Free PMC article.
Comparative analysis of the tumor microbiome, molecular profiles, and immune cell abundances by HPV status in mucosal head and neck cancers and their impact on survival.
Upadhyay R, Dhakal A, Wheeler C, Hoyd R, Jagjit Singh M, Karivedu V, Bhateja P, Bonomi M, Valentin S, Gamez ME, Konieczkowski DJ, Baliga S, Grecula JC, Blakaj DM, Gogineni E, Mitchell DL, Denko NC, Spakowicz D, Jhawar SR. Upadhyay R, et al. Among authors: spakowicz d. Cancer Biol Ther. 2024 Dec 31;25(1):2350249. doi: 10.1080/15384047.2024.2350249. Epub 2024 May 9. Cancer Biol Ther. 2024. PMID: 38722731 Free PMC article.
The tumor microbiome as a predictor of outcomes in patients with metastatic melanoma treated with immune checkpoint inhibitors.
Wheeler CE, Coleman SS 4th, Hoyd R, Denko L, Chan CHF, Churchman ML, Denko N, Dodd RD, Eljilany I, Hardikar S, Husain M, Ikeguchi AP, Jin N, Ma Q, McCarter MD, Osman AEG, Robinson LA, Singer EA, Tinoco G, Ulrich CM, Zakharia Y, Spakowicz D, Tarhini AA, Tan AC. Wheeler CE, et al. bioRxiv [Preprint]. 2023 May 25:2023.05.24.542123. doi: 10.1101/2023.05.24.542123. bioRxiv. 2023. PMID: 37292921 Free PMC article. Preprint.
A bioinformatics tool for identifying intratumoral microbes from the ORIEN dataset.
Wang C, Ma A, McNutt ME, Hoyd R, Wheeler CE, Robinson LA, Chan CHF, Zakharia Y, Dodd RD, Ulrich CM, Hardikar S, Churchman ML, Tarhini AA, Singer EA, Ikeguchi AP, McCarter MD, Denko N, Tinoco G, Husain M, Jin N, Osman AEG, Eljilany I, Tan AC, Coleman SS 4th, Denko L, Riedlinger G, Schneider BP, Spakowicz D, Ma Q. Wang C, et al. bioRxiv [Preprint]. 2023 May 24:2023.05.24.541982. doi: 10.1101/2023.05.24.541982. bioRxiv. 2023. PMID: 37292990 Free PMC article. Updated. Preprint.
The impact of antibiotic and proton pump inhibitor use at the time of adjuvant platinum-based chemotherapy on survival in patients with endometrial cancer.
Haight PJ, Kistenfeger Q, Riedinger CJ, Khadraoui W, Backes FJ, Bixel KL, Copeland LJ, Cohn DE, Cosgrove CM, O'Malley DM, Nagel CI, Spakowicz DJ, Chambers LM. Haight PJ, et al. Among authors: spakowicz dj. Gynecol Oncol. 2023 Nov;178:14-22. doi: 10.1016/j.ygyno.2023.09.005. Epub 2023 Sep 21. Gynecol Oncol. 2023. PMID: 37741201
Gut Microbiota Richness and Diversity Track With T Cell Aging in Healthy Adults.
Madison AA, Burd CE, Andridge R, Wilson SJ, Bailey MT, Belury MA, Spakowicz DJ, Malarkey WB, Kiecolt-Glaser JK. Madison AA, et al. Among authors: spakowicz dj. J Gerontol A Biol Sci Med Sci. 2024 Mar 1;79(3):glad276. doi: 10.1093/gerona/glad276. J Gerontol A Biol Sci Med Sci. 2024. PMID: 38123141
34 results