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Patient-specific, re-engineered cardiomyocyte model confirms the circumstance-dependent arrhythmia risk associated with the African-specific common SCN5A polymorphism p.S1103Y: Implications for the increased sudden deaths observed in black individuals during the COVID-19 pandemic.
Hamrick SK, John Kim CS, Tester DJ, Giudicessi JR, Ackerman MJ. Hamrick SK, et al. Heart Rhythm. 2022 May;19(5):822-827. doi: 10.1016/j.hrthm.2021.12.029. Epub 2021 Dec 31. Heart Rhythm. 2022. PMID: 34979239 Free article.
Acacetin, a Potent Transient Outward Current Blocker, May Be a Novel Therapeutic for KCND3-Encoded Kv4.3 Gain-of-Function-Associated J-Wave Syndromes.
Ye D, Zhou W, Hamrick SK, Tester DJ, Kim CSJ, Barajas-Martinez H, Hu D, Giudicessi JR, Antzelevitch C, Ackerman MJ. Ye D, et al. Among authors: hamrick sk. Circ Genom Precis Med. 2022 Oct;15(5):e003238. doi: 10.1161/CIRCGEN.120.003238. Epub 2022 Jul 12. Circ Genom Precis Med. 2022. PMID: 35861988 Free PMC article.
Characterization of N-terminal RYR2 variants outside CPVT1 hotspot regions using patient iPSCs reveal pathogenesis and therapeutic potential.
Stutzman MJ, Kim CSJ, Tester DJ, Hamrick SK, Dotzler SM, Giudicessi JR, Miotto MC, Gc JB, Frank J, Marks AR, Ackerman MJ. Stutzman MJ, et al. Among authors: hamrick sk. Stem Cell Reports. 2022 Sep 13;17(9):2023-2036. doi: 10.1016/j.stemcr.2022.07.002. Epub 2022 Aug 4. Stem Cell Reports. 2022. PMID: 35931078 Free PMC article.
Molecular characterization of the calcium release channel deficiency syndrome.
Tester DJ, Kim CSJ, Hamrick SK, Ye D, O'Hare BJ, Bombei HM, Fitzgerald KK, Haglund-Turnquist CM, Atkins DL, Nunez LAO, Law I, Temple J, Ackerman MJ. Tester DJ, et al. Among authors: hamrick sk. JCI Insight. 2020 Aug 6;5(15):e135952. doi: 10.1172/jci.insight.135952. JCI Insight. 2020. PMID: 32663189 Free PMC article.
Identification of a Novel Homozygous Multi-Exon Duplication in RYR2 Among Children With Exertion-Related Unexplained Sudden Deaths in the Amish Community.
Tester DJ, Bombei HM, Fitzgerald KK, Giudicessi JR, Pitel BA, Thorland EC, Russell BG, Hamrick SK, Kim CSJ, Haglund-Turnquist CM, Johnsrude CL, Atkins DL, Ochoa Nunez LA, Law I, Temple J, Ackerman MJ. Tester DJ, et al. Among authors: hamrick sk. JAMA Cardiol. 2020 Mar 1;5(3):13-18. doi: 10.1001/jamacardio.2019.5400. JAMA Cardiol. 2020. PMID: 31913406 Free PMC article.