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The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent.
Suchacki KJ, Thomas BJ, Ikushima YM, Chen KC, Fyfe C, Tavares AAS, Sulston RJ, Lovdel A, Woodward HJ, Han X, Mattiucci D, Brain EJ, Alcaide-Corral CJ, Kobayashi H, Gray GA, Whitfield PD, Stimson RH, Morton NM, Johnstone AM, Cawthorn WP. Suchacki KJ, et al. Among authors: kobayashi h. Elife. 2023 Apr 25;12:e88080. doi: 10.7554/eLife.88080. Elife. 2023. PMID: 37096321 Free PMC article.
Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis.
Watanuki S, Kobayashi H, Sugiura Y, Yamamoto M, Karigane D, Shiroshita K, Sorimachi Y, Fujita S, Morikawa T, Koide S, Oshima M, Nishiyama A, Murakami K, Haraguchi M, Tamaki S, Yamamoto T, Yabushita T, Tanaka Y, Nagamatsu G, Honda H, Okamoto S, Goda N, Tamura T, Nakamura-Ishizu A, Suematsu M, Iwama A, Suda T, Takubo K. Watanuki S, et al. Among authors: kobayashi h. Elife. 2024 Apr 4;12:RP87674. doi: 10.7554/eLife.87674. Elife. 2024. PMID: 38573813 Free PMC article.
SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production.
Watanuki S, Kobayashi H, Sugiura Y, Yamamoto M, Karigane D, Shiroshita K, Sorimachi Y, Morikawa T, Fujita S, Shide K, Haraguchi M, Tamaki S, Mikawa T, Kondoh H, Nakano H, Sumiyama K, Nagamatsu G, Goda N, Okamoto S, Nakamura-Ishizu A, Shimoda K, Suematsu M, Suda T, Takubo K. Watanuki S, et al. Among authors: kobayashi h. Cell Stem Cell. 2024 May 14:S1934-5909(24)00176-0. doi: 10.1016/j.stem.2024.04.023. Online ahead of print. Cell Stem Cell. 2024. PMID: 38772377
A culture platform to study quiescent hematopoietic stem cells following genome editing.
Shiroshita K, Kobayashi H, Watanuki S, Karigane D, Sorimachi Y, Fujita S, Tamaki S, Haraguchi M, Itokawa N, Aoyoama K, Koide S, Masamoto Y, Kobayashi K, Nakamura-Ishizu A, Kurokawa M, Iwama A, Okamoto S, Kataoka K, Takubo K. Shiroshita K, et al. Among authors: kobayashi h, kobayashi k. Cell Rep Methods. 2022 Dec 5;2(12):100354. doi: 10.1016/j.crmeth.2022.100354. eCollection 2022 Dec 19. Cell Rep Methods. 2022. PMID: 36590688 Free PMC article.
Long-Term pemafibrate treatment exhibits limited impact on body fat mass in patients with hypertriglyceridemia accompanying NAFLD.
Iwadare T, Kimura T, Kunimoto H, Okumura T, Wakabayashi SI, Kobayashi H, Yamashita Y, Sugiura A, Tanaka N, Umemura T. Iwadare T, et al. Among authors: kobayashi h. Front Endocrinol (Lausanne). 2024 May 17;15:1329294. doi: 10.3389/fendo.2024.1329294. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38828415 Free PMC article.
9,334 results