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Acylation of the Incretin Peptide Exendin-4 Directly Impacts Glucagon-Like Peptide-1 Receptor Signaling and Trafficking.
Lucey M, Ashik T, Marzook A, Wang Y, Goulding J, Oishi A, Broichhagen J, Hodson DJ, Minnion J, Elani Y, Jockers R, Briddon SJ, Bloom SR, Tomas A, Jones B. Lucey M, et al. Among authors: tomas a. Mol Pharmacol. 2021 Oct;100(4):319-334. doi: 10.1124/molpharm.121.000270. Epub 2021 Jul 27. Mol Pharmacol. 2021. PMID: 34315812 Free PMC article.
Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells.
Fang Z, Chen S, Manchanda Y, Bitsi S, Pickford P, David A, Shchepinova MM, Corrêa IR Jr, Hodson DJ, Broichhagen J, Tate EW, Reimann F, Salem V, Rutter GA, Tan T, Bloom SR, Tomas A, Jones B. Fang Z, et al. Among authors: tomas a. Int J Mol Sci. 2020 Nov 9;21(21):8404. doi: 10.3390/ijms21218404. Int J Mol Sci. 2020. PMID: 33182425 Free PMC article.
Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion.
Georgiadou E, Muralidharan C, Martinez M, Chabosseau P, Akalestou E, Tomas A, Wern FYS, Stylianides T, Wretlind A, Legido-Quigley C, Jones B, Lopez-Noriega L, Xu Y, Gu G, Alsabeeh N, Cruciani-Guglielmacci C, Magnan C, Ibberson M, Leclerc I, Ali Y, Soleimanpour SA, Linnemann AK, Rodriguez TA, Rutter GA. Georgiadou E, et al. Among authors: tomas a. Diabetes. 2022 Jul 1;71(7):1472-1489. doi: 10.2337/db21-0800. Diabetes. 2022. PMID: 35472764 Free PMC article.
Hepatocyte cholesterol content modulates glucagon receptor signalling.
McGlone ER, Ansell TB, Dunsterville C, Song W, Carling D, Tomas A, Bloom SR, Sansom MSP, Tan T, Jones B. McGlone ER, et al. Among authors: tomas a. Mol Metab. 2022 Sep;63:101530. doi: 10.1016/j.molmet.2022.101530. Epub 2022 Jun 16. Mol Metab. 2022. PMID: 35718339 Free PMC article.
452 results