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Oncogenic CDK13 mutations impede nuclear RNA surveillance.
Insco ML, Abraham BJ, Dubbury SJ, Kaltheuner IH, Dust S, Wu C, Chen KY, Liu D, Bellaousov S, Cox AM, Martin BJE, Zhang T, Ludwig CG, Fabo T, Modhurima R, Esgdaille DE, Henriques T, Brown KM, Chanock SJ, Geyer M, Adelman K, Sharp PA, Young RA, Boutz PL, Zon LI. Insco ML, et al. Among authors: liu d. Science. 2023 Apr 21;380(6642):eabn7625. doi: 10.1126/science.abn7625. Epub 2023 Apr 21. Science. 2023. PMID: 37079685 Free PMC article.
DNA capture by a CRISPR-Cas9-guided adenine base editor.
Lapinaite A, Knott GJ, Palumbo CM, Lin-Shiao E, Richter MF, Zhao KT, Beal PA, Liu DR, Doudna JA. Lapinaite A, et al. Science. 2020 Jul 31;369(6503):566-571. doi: 10.1126/science.abb1390. Science. 2020. PMID: 32732424 Free PMC article.
Base editing rescue of spinal muscular atrophy in cells and in mice.
Arbab M, Matuszek Z, Kray KM, Du A, Newby GA, Blatnik AJ, Raguram A, Richter MF, Zhao KT, Levy JM, Shen MW, Arnold WD, Wang D, Xie J, Gao G, Burghes AHM, Liu DR. Arbab M, et al. Among authors: liu dr. Science. 2023 Apr 21;380(6642):eadg6518. doi: 10.1126/science.adg6518. Epub 2023 Apr 14. Science. 2023. PMID: 36996170 Free PMC article.
LC/MS analysis of cellular RNA reveals NAD-linked RNA.
Chen YG, Kowtoniuk WE, Agarwal I, Shen Y, Liu DR. Chen YG, et al. Nat Chem Biol. 2009 Dec;5(12):879-81. doi: 10.1038/nchembio.235. Epub 2009 Oct 11. Nat Chem Biol. 2009. PMID: 19820715 Free PMC article.
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