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Dysregulation of systemic soluble immune checkpoints in early breast cancer is attenuated following administration of neoadjuvant chemotherapy and is associated with recovery of CD27, CD28, CD40, CD80, ICOS and GITR and substantially increased levels of PD-L1, LAG-3 and TIM-3.
Rapoport BL, Steel HC, Benn CA, Nayler S, Smit T, Heyman L, Theron AJ, Hlatshwayo N, Kwofie LLI, Meyer PWA, Anderson R. Rapoport BL, et al. Among authors: hlatshwayo n. Front Oncol. 2023 Mar 30;13:1097309. doi: 10.3389/fonc.2023.1097309. eCollection 2023. Front Oncol. 2023. PMID: 37064132 Free PMC article.
Systemic Immune Dysregulation in Early Breast Cancer Is Associated With Decreased Plasma Levels of Both Soluble Co-Inhibitory and Co-Stimulatory Immune Checkpoint Molecules.
Rapoport BL, Steel HC, Hlatshwayo N, Theron AJ, Meyer PWA, Nayler S, Benn CA, Smit T, Kwofie LLI, Heyman L, Anderson R. Rapoport BL, et al. Among authors: hlatshwayo n. Front Immunol. 2022 May 23;13:823842. doi: 10.3389/fimmu.2022.823842. eCollection 2022. Front Immunol. 2022. PMID: 35677046 Free PMC article.
Rivaroxaban in Rheumatic Heart Disease-Associated Atrial Fibrillation.
Connolly SJ, Karthikeyan G, Ntsekhe M, Haileamlak A, El Sayed A, El Ghamrawy A, Damasceno A, Avezum A, Dans AML, Gitura B, Hu D, Kamanzi ER, Maklady F, Fana G, Gonzalez-Hermosillo JA, Musuku J, Kazmi K, Zühlke L, Gondwe L, Ma C, Paniagua M, Ogah OS, Molefe-Baikai OJ, Lwabi P, Chillo P, Sharma SK, Cabral TTJ, Tarhuni WM, Benz A, van Eikels M, Krol A, Pattath D, Balasubramanian K, Rangarajan S, Ramasundarahettige C, Mayosi B, Yusuf S; INVICTUS Investigators. Connolly SJ, et al. N Engl J Med. 2022 Sep 15;387(11):978-988. doi: 10.1056/NEJMoa2209051. Epub 2022 Aug 28. N Engl J Med. 2022. PMID: 36036525 Clinical Trial.
Effect of slow-release indapamide and perindopril compared with amlodipine on 24-hour blood pressure and left ventricular mass in hypertensive patients of African ancestry.
Libhaber EN, Libhaber CD, Candy GP, Sliwa K, Kachope J, Hlatshwayo NM, Puane MO, Woodiwiss AJ, Norton GR, Essop MR, Sareli P. Libhaber EN, et al. Among authors: hlatshwayo nm. Am J Hypertens. 2004 May;17(5 Pt 1):428-32. doi: 10.1016/j.amjhyper.2004.02.010. Am J Hypertens. 2004. PMID: 15110902 Clinical Trial.