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Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells.
Quintela M, James DW, Pociute A, Powell L, Edwards K, Coombes Z, Garcia J, Garton N, Das N, Lutchman-Singh K, Margarit L, Beynon AL, Rioja I, Prinjha RK, Harker NR, Gonzalez D, Conlan RS, Francis LW. Quintela M, et al. Among authors: lutchman singh k. Clin Epigenetics. 2023 Apr 15;15(1):63. doi: 10.1186/s13148-023-01477-x. Clin Epigenetics. 2023. PMID: 37060086 Free PMC article.
Surgical decision making in premenopausal BRCA carriers considering risk-reducing early salpingectomy or salpingo-oophorectomy: a qualitative study.
Gaba F, Goyal S, Marks D, Chandrasekaran D, Evans O, Robbani S, Tyson C, Legood R, Saridogan E, McCluggage WG, Hanson H, Singh N, Evans DG, Menon U, Manchanda R; PROTECTOR team. Gaba F, et al. J Med Genet. 2022 Feb;59(2):122-132. doi: 10.1136/jmedgenet-2020-107501. Epub 2021 Feb 10. J Med Genet. 2022. PMID: 33568437 Free PMC article.
Cu isotope ratios are meaningful in ovarian cancer diagnosis.
Toubhans B, Gourlan AT, Telouk P, Lutchman-Singh K, Francis LW, Conlan RS, Margarit L, Gonzalez D, Charlet L. Toubhans B, et al. J Trace Elem Med Biol. 2020 Dec;62:126611. doi: 10.1016/j.jtemb.2020.126611. Epub 2020 Jul 3. J Trace Elem Med Biol. 2020. PMID: 32652467 Free article.
Dinaciclib, a Bimodal Agent Effective against Endometrial Cancer.
Howard D, James D, Murphy K, Garcia-Parra J, Pan-Castillo B, Rex S, Moul A, Jones E, Bilbao-Asensio M, Michue-Seijas S, Lutchman-Singh K, Margarit L, Francis LW, Rees P, Gonzalez D, Conlan RS. Howard D, et al. Among authors: lutchman singh k. Cancers (Basel). 2021 Mar 6;13(5):1135. doi: 10.3390/cancers13051135. Cancers (Basel). 2021. PMID: 33800911 Free PMC article.
Dinaciclib as an effective pan-cyclin dependent kinase inhibitor in platinum resistant ovarian cancer.
Howard D, James D, Garcia-Parra J, Pan-Castillo B, Worthington J, Williams N, Coombes Z, Rees SC, Lutchman-Singh K, Francis LW, Rees P, Margarit L, Conlan RS, Gonzalez D. Howard D, et al. Among authors: lutchman singh k. Front Oncol. 2022 Nov 25;12:1014280. doi: 10.3389/fonc.2022.1014280. eCollection 2022. Front Oncol. 2022. PMID: 36505806 Free PMC article.
24 results