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Atypical teratoid/rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities.
Oncogene. 2023 May;42(20):1661-1671. doi: 10.1038/s41388-023-02681-y. Epub 2023 Apr 5.
Oncogene. 2023.
PMID: 37020038
Free PMC article.
In vitro Modeling of Embryonal Tumors.
Custers L, Paassen I, Drost J.
Custers L, et al. Among authors: paassen i.
Front Cell Dev Biol. 2021 Feb 26;9:640633. doi: 10.3389/fcell.2021.640633. eCollection 2021.
Front Cell Dev Biol. 2021.
PMID: 33718380
Free PMC article.
Review.
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Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors.
Calandrini C, van Hooff SR, Paassen I, Ayyildiz D, Derakhshan S, Dolman MEM, Langenberg KPS, van de Ven M, de Heus C, Liv N, Kool M, de Krijger RR, Tytgat GAM, van den Heuvel-Eibrink MM, Molenaar JJ, Drost J.
Calandrini C, et al. Among authors: paassen i.
Cell Rep. 2021 Aug 24;36(8):109568. doi: 10.1016/j.celrep.2021.109568.
Cell Rep. 2021.
PMID: 34433038
Free article.
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CRISPR-Cas9 Library Screening Identifies Novel Molecular Vulnerabilities in KMT2A-Rearranged Acute Lymphoblastic Leukemia.
Schneider P, Wander P, Arentsen-Peters STCJM, Vrenken KS, Rockx-Brouwer D, Adriaanse FRS, Hoeve V, Paassen I, Drost J, Pieters R, Stam RW.
Schneider P, et al. Among authors: paassen i.
Int J Mol Sci. 2023 Aug 25;24(17):13207. doi: 10.3390/ijms241713207.
Int J Mol Sci. 2023.
PMID: 37686014
Free PMC article.
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SMARCB1 loss activates patient-specific distal oncogenic enhancers in malignant rhabdoid tumors.
Liu NQ, Paassen I, Custers L, Zeller P, Teunissen H, Ayyildiz D, He J, Buhl JL, Hoving EW, van Oudenaarden A, de Wit E, Drost J.
Liu NQ, et al. Among authors: paassen i.
Nat Commun. 2023 Dec 1;14(1):7762. doi: 10.1038/s41467-023-43498-3.
Nat Commun. 2023.
PMID: 38040699
Free PMC article.
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