Bhabha G - Search Results

1

De novo design of modular peptide-binding proteins by superhelical matching.

Wu K, Bai H, Chang YT, Redler R, McNally KE, Sheffler W, Brunette TJ, Hicks DR, Morgan TE, Stevens TJ, Broerman A, Goreshnik I, DeWitt M, Chow CM, Shen Y, Stewart L, Derivery E, Silva DA, Bhabha G, Ekiert DC, Baker D. Wu K, et al. Among authors: bhabha g. Nature. 2023 Apr;616(7957):581-589. doi: 10.1038/s41586-023-05909-9. Epub 2023 Apr 5. Nature. 2023. PMID: 37020023 Free PMC article.

2

The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types.

Daniloski Z, Jordan TX, Ilmain JK, Guo X, Bhabha G, tenOever BR, Sanjana NE. Daniloski Z, et al. Among authors: bhabha g. bioRxiv [Preprint]. 2020 Jul 7:2020.06.14.151357. doi: 10.1101/2020.06.14.151357. bioRxiv. 2020. PMID: 32587969 Free PMC article. Updated. Preprint.

3

The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types.

Daniloski Z, Jordan TX, Ilmain JK, Guo X, Bhabha G, tenOever BR, Sanjana NE. Daniloski Z, et al. Among authors: bhabha g. Elife. 2021 Feb 11;10:e65365. doi: 10.7554/eLife.65365. Elife. 2021. PMID: 33570490 Free PMC article.

4

A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.

Bhabha G, Lee J, Ekiert DC, Gam J, Wilson IA, Dyson HJ, Benkovic SJ, Wright PE. Bhabha G, et al. Science. 2011 Apr 8;332(6026):234-8. doi: 10.1126/science.1198542. Science. 2011. PMID: 21474759 Free PMC article.

5

Cross-neutralization of influenza A viruses mediated by a single antibody loop.

Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, Khayat R, Lee JH, Dillon MA, O'Neil RE, Faynboym AM, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, Lerner RA, Bhatt RR, Wilson IA. Ekiert DC, et al. Among authors: bhabha g. Nature. 2012 Sep 27;489(7417):526-32. doi: 10.1038/nature11414. Epub 2012 Sep 16. Nature. 2012. PMID: 22982990 Free PMC article.

6

Divergent evolution of protein conformational dynamics in dihydrofolate reductase.

Bhabha G, Ekiert DC, Jennewein M, Zmasek CM, Tuttle LM, Kroon G, Dyson HJ, Godzik A, Wilson IA, Wright PE. Bhabha G, et al. Nat Struct Mol Biol. 2013 Nov;20(11):1243-9. doi: 10.1038/nsmb.2676. Epub 2013 Sep 29. Nat Struct Mol Biol. 2013. PMID: 24077226 Free PMC article.

7

Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts.

Liu Y, Tan YL, Zhang X, Bhabha G, Ekiert DC, Genereux JC, Cho Y, Kipnis Y, Bjelic S, Baker D, Kelly JW. Liu Y, et al. Among authors: bhabha g. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4449-54. doi: 10.1073/pnas.1323268111. Epub 2014 Mar 3. Proc Natl Acad Sci U S A. 2014. PMID: 24591605 Free PMC article.

8

De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.

Liu Y, Zhang X, Tan YL, Bhabha G, Ekiert DC, Kipnis Y, Bjelic S, Baker D, Kelly JW. Liu Y, et al. Among authors: bhabha g. J Am Chem Soc. 2014 Sep 24;136(38):13102-5. doi: 10.1021/ja5056356. Epub 2014 Sep 11. J Am Chem Soc. 2014. PMID: 25209927 Free PMC article.

9

Exploring the repeat protein universe through computational protein design.

Brunette TJ, Parmeggiani F, Huang PS, Bhabha G, Ekiert DC, Tsutakawa SE, Hura GL, Tainer JA, Baker D. Brunette TJ, et al. Among authors: bhabha g. Nature. 2015 Dec 24;528(7583):580-4. doi: 10.1038/nature16162. Epub 2015 Dec 16. Nature. 2015. PMID: 26675729 Free PMC article.

10

Architectures of Lipid Transport Systems for the Bacterial Outer Membrane.

Ekiert DC, Bhabha G, Isom GL, Greenan G, Ovchinnikov S, Henderson IR, Cox JS, Vale RD. Ekiert DC, et al. Among authors: bhabha g. Cell. 2017 Apr 6;169(2):273-285.e17. doi: 10.1016/j.cell.2017.03.019. Cell. 2017. PMID: 28388411 Free PMC article.

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