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Effects of a ketogenic and low-fat diet on the human metabolome, microbiome, and foodome in adults at risk for Alzheimer's disease.
Dilmore AH, Martino C, Neth BJ, West KA, Zemlin J, Rahman G, Panitchpakdi M, Meehan MJ, Weldon KC, Blach C, Schimmel L, Kaddurah-Daouk R, Dorrestein PC, Knight R, Craft S; Alzheimer's Gut Microbiome Project Consortium. Dilmore AH, et al. Among authors: schimmel l. Alzheimers Dement. 2023 Nov;19(11):4805-4816. doi: 10.1002/alz.13007. Epub 2023 Apr 5. Alzheimers Dement. 2023. PMID: 37017243
Comparative Metabolomics and Microbiome Analysis of Ethanol versus OMNImet/gene•GUT Fecal Stabilization.
Isokääntä H, Pinto da Silva L, Karu N, Kallonen T, Aatsinki AK, Hankemeier T, Schimmel L, Diaz E, Hyötyläinen T, Dorrestein PC, Knight R, Orešič M, Kaddurah-Daouk R, Dickens AM, Lamichhane S. Isokääntä H, et al. Among authors: schimmel l. Anal Chem. 2024 May 23. doi: 10.1021/acs.analchem.3c04436. Online ahead of print. Anal Chem. 2024. PMID: 38782403
A Modified Mediterranean Ketogenic Diet mitigates modifiable risk factors of Alzheimer's Disease: a serum and CSF-based metabolic analysis.
Schweickart A, Batra R, Neth BJ, Martino C, Shenhav L, Zhang AR, Shi P, Karu N, Huynh K, Meikle PJ, Schimmel L, Dilmore AH, Blennow K, Zetterberg H, Blach C, Dorrestein PC, Knight R; Alzheimer’s Gut Microbiome Project Consortium; Craft S, Kaddurah-Daouk R, Krumsiek J. Schweickart A, et al. Among authors: schimmel l. medRxiv [Preprint]. 2023 Nov 27:2023.11.27.23298990. doi: 10.1101/2023.11.27.23298990. medRxiv. 2023. PMID: 38076824 Free PMC article. Preprint.
Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis.
Jin Y, Ding Y, Richards M, Kaakinen M, Giese W, Baumann E, Szymborska A, Rosa A, Nordling S, Schimmel L, Akmeriç EB, Pena A, Nwadozi E, Jamalpour M, Holstein K, Sáinz-Jaspeado M, Bernabeu MO, Welsh M, Gordon E, Franco CA, Vestweber D, Eklund L, Gerhardt H, Claesson-Welsh L. Jin Y, et al. Among authors: schimmel l. Nat Cardiovasc Res. 2022 Dec 7;1(12):1156-1173. doi: 10.1038/s44161-022-00172-z. Nat Cardiovasc Res. 2022. PMID: 37936984 Free PMC article.
An E-cadherin-actin clutch translates the mechanical force of cortical flow for cell-cell contact to inhibit epithelial cell locomotion.
Noordstra I, Hermoso MD, Schimmel L, Bonfim-Melo A, Currin-Ross D, Duong CN, Kalappurakkal JM, Morris RG, Vestweber D, Mayor S, Gordon E, Roca-Cusachs P, Yap AS. Noordstra I, et al. Among authors: schimmel l. Dev Cell. 2023 Sep 25;58(18):1748-1763.e6. doi: 10.1016/j.devcel.2023.06.011. Epub 2023 Jul 21. Dev Cell. 2023. PMID: 37480844
Endothelial cells are not productively infected by SARS-CoV-2.
Schimmel L, Chew KY, Stocks CJ, Yordanov TE, Essebier P, Kulasinghe A, Monkman J, Dos Santos Miggiolaro AFR, Cooper C, de Noronha L, Schroder K, Lagendijk AK, Labzin LI, Short KR, Gordon EJ. Schimmel L, et al. Clin Transl Immunology. 2021 Oct 24;10(10):e1350. doi: 10.1002/cti2.1350. eCollection 2021. Clin Transl Immunology. 2021. PMID: 34721846 Free PMC article.
Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration.
Arts JJ, Mahlandt EK, Grönloh ML, Schimmel L, Noordstra I, Gordon E, van Steen AC, Tol S, Walzog B, van Rijssel J, Nolte MA, Postma M, Khuon S, Heddleston JM, Wait E, Chew TL, Winter M, Montanez E, Goedhart J, van Buul JD. Arts JJ, et al. Among authors: schimmel l. Elife. 2021 Aug 25;10:e66074. doi: 10.7554/eLife.66074. Elife. 2021. PMID: 34431475 Free PMC article.
Endothelial Focal Adhesions Are Functional Obstacles for Leukocytes During Basolateral Crawling.
Arts JJG, Mahlandt EK, Schimmel L, Grönloh MLB, van der Niet S, Klein BJAM, Fernandez-Borja M, van Geemen D, Huveneers S, van Rijssel J, Goedhart J, van Buul JD. Arts JJG, et al. Among authors: schimmel l. Front Immunol. 2021 May 18;12:667213. doi: 10.3389/fimmu.2021.667213. eCollection 2021. Front Immunol. 2021. PMID: 34084168 Free PMC article.
31 results