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Study protocol of a randomised, double-blind, placebo-controlled, two-arm parallel-group, multi-centre phase 3 pivotal trial to investigate the efficacy and safety of recombinant human alkaline phosphatase for treatment of patients with sepsis-associated acute kidney injury.
Pickkers P, Angus DC, Arend J, Bellomo R, van den Berg E, Bernholz J, Bestle M, Broglio K, Carlsen J, Doig CJ, Ferrer R, Joannidis M, Francois B, Doi K, Kellum JA, Laterre PF, Liu K, Mehta RL, Murray PT, Ostermann M, Pettilä V, Richards S, Young P, Zarbock A, Kjølbye AL. Pickkers P, et al. Among authors: pettila v. BMJ Open. 2023 Apr 3;13(4):e065613. doi: 10.1136/bmjopen-2022-065613. BMJ Open. 2023. PMID: 37012016 Free PMC article.
Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial.
Abraham E, Reinhart K, Opal S, Demeyer I, Doig C, Rodriguez AL, Beale R, Svoboda P, Laterre PF, Simon S, Light B, Spapen H, Stone J, Seibert A, Peckelsen C, De Deyne C, Postier R, Pettilä V, Sprung CL, Artigas A, Percell SR, Shu V, Zwingelstein C, Tobias J, Poole L, Stolzenbach JC, Creasey AA; OPTIMIST Trial Study Group. Abraham E, et al. Among authors: pettila v. JAMA. 2003 Jul 9;290(2):238-47. doi: 10.1001/jama.290.2.238. JAMA. 2003. PMID: 12851279 Clinical Trial.
Comparing the effect of hydroxyethyl starch 130/0.4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S--Scandinavian Starch for Severe Sepsis/Septic Shock trial): study protocol, design and rationale for a double-blinded, randomised clinical trial.
Perner A, Haase N, Wetterslev J, Aneman A, Tenhunen J, Guttormsen AB, Klemenzson G, Pott F, Bødker KD, Bådstøløkken PM, Bendtsen A, Søe-Jensen P, Tousi H, Bestle M, Pawlowicz M, Winding R, Bülow HH, Kancir C, Steensen M, Nielsen J, Fogh B, Madsen KR, Larsen NH, Carlsson M, Wiis J, Petersen JA, Iversen S, Schøidt O, Leivdal S, Berezowicz P, Pettilä V, Ruokonen E, Klepstad P, Karlsson S, Kaukonen M, Rutanen J, Karason S, Kjældgaard AL, Holst LB, Wernerman J; Scandinavian Critical Care Trials Group. Perner A, et al. Among authors: pettila v. Trials. 2011 Jan 27;12:24. doi: 10.1186/1745-6215-12-24. Trials. 2011. PMID: 21269526 Free PMC article. Clinical Trial.
Acute kidney injury in patients with influenza A (H1N1) 2009.
Pettilä V, Webb SA, Bailey M, Howe B, Seppelt IM, Bellomo R. Pettilä V, et al. Intensive Care Med. 2011 May;37(5):763-7. doi: 10.1007/s00134-011-2166-8. Epub 2011 Mar 11. Intensive Care Med. 2011. PMID: 21394631
Understanding acute kidney injury in sepsis.
Pettilä V, Bellomo R. Pettilä V, et al. Intensive Care Med. 2014 Jul;40(7):1018-20. doi: 10.1007/s00134-014-3313-9. Epub 2014 May 6. Intensive Care Med. 2014. PMID: 24797686 No abstract available.
Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial.
Nichol A, French C, Little L, Haddad S, Presneill J, Arabi Y, Bailey M, Cooper DJ, Duranteau J, Huet O, Mak A, McArthur C, Pettilä V, Skrifvars M, Vallance S, Varma D, Wills J, Bellomo R; EPO-TBI Investigators; ANZICS Clinical Trials Group. Nichol A, et al. Among authors: pettila v. Lancet. 2015 Dec 19;386(10012):2499-506. doi: 10.1016/S0140-6736(15)00386-4. Epub 2015 Oct 6. Lancet. 2015. PMID: 26452709 Clinical Trial.
Fluid management in acute kidney injury.
Perner A, Prowle J, Joannidis M, Young P, Hjortrup PB, Pettilä V. Perner A, et al. Among authors: pettila v. Intensive Care Med. 2017 Jun;43(6):807-815. doi: 10.1007/s00134-017-4817-x. Epub 2017 May 3. Intensive Care Med. 2017. PMID: 28470347 Review.
357 results