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STIM1 ablation impairs exercise-induced physiological cardiac hypertrophy and dysregulates autophagy in mouse hearts.
Bonilla IM, Baine S, Pokrass A, Mariángelo JIE, Kalyanasundaram A, Bogdanov V, Mezache L, Sakuta G, Beard CM, Belevych A, Tikunova S, Terentyeva R, Terentyev D, Davis J, Veeraraghavan R, Carnes CA, Györke S. Bonilla IM, et al. Among authors: kalyanasundaram a. J Appl Physiol (1985). 2023 May 1;134(5):1287-1299. doi: 10.1152/japplphysiol.00363.2022. Epub 2023 Mar 30. J Appl Physiol (1985). 2023. PMID: 36995910 Free PMC article.
A mutation in calsequestrin, CASQ2D307H, impairs Sarcoplasmic Reticulum Ca2+ handling and causes complex ventricular arrhythmias in mice.
Dirksen WP, Lacombe VA, Chi M, Kalyanasundaram A, Viatchenko-Karpinski S, Terentyev D, Zhou Z, Vedamoorthyrao S, Li N, Chiamvimonvat N, Carnes CA, Franzini-Armstrong C, Györke S, Periasamy M. Dirksen WP, et al. Among authors: kalyanasundaram a. Cardiovasc Res. 2007 Jul 1;75(1):69-78. doi: 10.1016/j.cardiores.2007.03.002. Epub 2007 Mar 12. Cardiovasc Res. 2007. PMID: 17449018 Free PMC article.
Functional consequences of stably expressing a mutant calsequestrin (CASQ2D307H) in the CASQ2 null background.
Kalyanasundaram A, Viatchenko-Karpinski S, Belevych AE, Lacombe VA, Hwang HS, Knollmann BC, Gyorke S, Periasamy M. Kalyanasundaram A, et al. Am J Physiol Heart Circ Physiol. 2012 Jan 1;302(1):H253-61. doi: 10.1152/ajpheart.00578.2011. Epub 2011 Oct 7. Am J Physiol Heart Circ Physiol. 2012. PMID: 21984545 Free PMC article.
We recently reported that the mutant CASQ2(D307H) protein can be stably expressed in CASQ2 null hearts, and it targets appropriately to the junctional SR (Kalyanasundaram A, Bal NC, Franzini-Armstrong C, Knollmann BC, Periasamy M. ...
We recently reported that the mutant CASQ2(D307H) protein can be stably expressed in CASQ2 null hearts, and it targets appropriately to the …
Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1.
Glukhov AV, Kalyanasundaram A, Lou Q, Hage LT, Hansen BJ, Belevych AE, Mohler PJ, Knollmann BC, Periasamy M, Györke S, Fedorov VV. Glukhov AV, et al. Among authors: kalyanasundaram a. Eur Heart J. 2015 Mar 14;36(11):686-97. doi: 10.1093/eurheartj/eht452. Epub 2013 Nov 11. Eur Heart J. 2015. PMID: 24216388 Free PMC article.
Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping.
Lou Q, Hansen BJ, Fedorenko O, Csepe TA, Kalyanasundaram A, Li N, Hage LT, Glukhov AV, Billman GE, Weiss R, Mohler PJ, Györke S, Biesiadecki BJ, Carnes CA, Fedorov VV. Lou Q, et al. Among authors: kalyanasundaram a. Circulation. 2014 Jul 22;130(4):315-24. doi: 10.1161/CIRCULATIONAHA.113.007086. Epub 2014 May 16. Circulation. 2014. PMID: 24838362 Free PMC article.
Impaired neuronal sodium channels cause intranodal conduction failure and reentrant arrhythmias in human sinoatrial node.
Li N, Kalyanasundaram A, Hansen BJ, Artiga EJ, Sharma R, Abudulwahed SH, Helfrich KM, Rozenberg G, Wu PJ, Zakharkin S, Gyorke S, Janssen PM, Whitson BA, Mokadam NA, Biesiadecki BJ, Accornero F, Hummel JD, Mohler PJ, Dobrzynski H, Zhao J, Fedorov VV. Li N, et al. Among authors: kalyanasundaram a. Nat Commun. 2020 Jan 24;11(1):512. doi: 10.1038/s41467-019-14039-8. Nat Commun. 2020. PMID: 31980605 Free PMC article.
118 results