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Proteomic Characterization of Acute Kidney Injury in Patients Hospitalized with SARS-CoV2 Infection.
Nadkami G, Paranjpe I, Jayaraman P, Su CY, Zhou S, Chen S, Valle DD, Thompson R, Kenigsberg E, Zhao S, Jaladanki S, Chaudhary K, Ascolillo S, Vaid A, Gonzalez-Kozlova E, Kumar A, Paranjpe M, O'Hagan R, Kamat S, Gulamali F, Kauffman J, Xie H, Harris J, Patel M, Argueta K, Batchelor C, Nie K, Dellepiane S, Scott L, Levin M, He J, Suárez-Fariñas M, Coca S, Chan L, Azeloglu E, Schadt E, Beckmann N, Gnjatic S, Merad M, Kim-Schulze S, Richards JB, Glicksberg B, Charney A. Nadkami G, et al. Among authors: azeloglu e. Res Sq [Preprint]. 2023 Mar 16:rs.3.rs-2379226. doi: 10.21203/rs.3.rs-2379226/v1. Res Sq. 2023. PMID: 36993735 Free PMC article. Updated. Preprint.
Plasminogenuria is associated with podocyte injury, edema, and kidney dysfunction in incident glomerular disease.
Egerman MA, Wong JS, Runxia T, Mosoyan G, Chauhan K, Reyes-Bahamonde J, Anandakrishnan N, Wong NJ, Bagiella E, Salem F, Meliambro K, Li H, Azeloglu EU, Coca SG, Campbell KN, Raij L. Egerman MA, et al. Among authors: azeloglu eu. FASEB J. 2020 Dec;34(12):16191-16204. doi: 10.1096/fj.202000413R. Epub 2020 Oct 18. FASEB J. 2020. PMID: 33070369 Free PMC article.
Proteomic characterization of acute kidney injury in patients hospitalized with SARS-CoV2 infection.
Paranjpe I, Jayaraman P, Su CY, Zhou S, Chen S, Thompson R, Del Valle DM, Kenigsberg E, Zhao S, Jaladanki S, Chaudhary K, Ascolillo S, Vaid A, Gonzalez-Kozlova E, Kauffman J, Kumar A, Paranjpe M, Hagan RO, Kamat S, Gulamali FF, Xie H, Harris J, Patel M, Argueta K, Batchelor C, Nie K, Dellepiane S, Scott L, Levin MA, He JC, Suarez-Farinas M, Coca SG, Chan L, Azeloglu EU, Schadt E, Beckmann N, Gnjatic S, Merad M, Kim-Schulze S, Richards B, Glicksberg BS, Charney AW, Nadkarni GN. Paranjpe I, et al. Among authors: azeloglu eu. Commun Med (Lond). 2023 Jun 12;3(1):81. doi: 10.1038/s43856-023-00307-8. Commun Med (Lond). 2023. PMID: 37308534 Free PMC article.
Patient-Specific Pharmacokinetics and Dasatinib Nephrotoxicity.
Adegbite BO, Abramson MH, Gutgarts V, Musteata FM, Chauhan K, Muwonge AN, Meliambro KA, Salvatore SP, El Ghaity-Beckley S, Kremyanskaya M, Marcellino B, Mascarenhas JO, Campbell KN, Chan L, Coca SG, Berman EM, Jaimes EA, Azeloglu EU. Adegbite BO, et al. Clin J Am Soc Nephrol. 2023 Sep 1;18(9):1175-1185. doi: 10.2215/CJN.0000000000000219. Epub 2023 Jun 29. Clin J Am Soc Nephrol. 2023. PMID: 37382967
Deep learning on electronic medical records identifies distinct subphenotypes of diabetic kidney disease driven by genetic variations in the Rho pathway.
Paranjpe I, Wang X, Anandakrishnan N, Haydak JC, Van Vleck T, DeFronzo S, Li Z, Mendoza A, Liu R, Fu J, Forrest I, Zhou W, Lee K, O'Hagan R, Dellepiane S, Menon KM, Gulamali F, Kamat S, Gusella GL, Charney AW, Hofer I, Cho JH, Do R, Glicksberg BS, He JC, Nadkarni GN, Azeloglu EU. Paranjpe I, et al. Among authors: azeloglu eu. medRxiv [Preprint]. 2023 Sep 7:2023.09.06.23295120. doi: 10.1101/2023.09.06.23295120. medRxiv. 2023. PMID: 37732187 Free PMC article. Preprint.
Integrated multiomics implicates dysregulation of ECM and cell adhesion pathways as drivers of severe COVID-associated kidney injury.
Anandakrishnan N, Yi Z, Sun Z, Liu T, Haydak J, Eddy S, Jayaraman P, DeFronzo S, Saha A, Sun Q, Yang D, Mendoza A, Mosoyan G, Wen HH, Schaub JA, Fu J, Kehrer T, Menon R, Otto EA, Godfrey B, Suarez-Farinas M, Leffters S, Twumasi A, Meliambro K, Charney AW, García-Sastre A, Campbell KN, Gusella GL, He JC, Miorin L, Nadkarni GN, Wisnivesky J, Li H, Kretzler M, Coca SG, Chan L, Zhang W, Azeloglu EU. Anandakrishnan N, et al. Among authors: azeloglu eu. medRxiv [Preprint]. 2024 Mar 19:2024.03.18.24304401. doi: 10.1101/2024.03.18.24304401. medRxiv. 2024. PMID: 38562892 Free PMC article. Preprint.
Systems pharmacology of adverse event mitigation by drug combinations.
Zhao S, Nishimura T, Chen Y, Azeloglu EU, Gottesman O, Giannarelli C, Zafar MU, Benard L, Badimon JJ, Hajjar RJ, Goldfarb J, Iyengar R. Zhao S, et al. Sci Transl Med. 2013 Oct 9;5(206):206ra140. doi: 10.1126/scitranslmed.3006548. Sci Transl Med. 2013. PMID: 24107779 Free PMC article.
Interconnected network motifs control podocyte morphology and kidney function.
Azeloglu EU, Hardy SV, Eungdamrong NJ, Chen Y, Jayaraman G, Chuang PY, Fang W, Xiong H, Neves SR, Jain MR, Li H, Ma'ayan A, Gordon RE, He JC, Iyengar R. Azeloglu EU, et al. Sci Signal. 2014 Feb 4;7(311):ra12. doi: 10.1126/scisignal.2004621. Sci Signal. 2014. PMID: 24497609 Free PMC article.
83 results