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Both moderate- and high-intensity exercise training increase intramyocellular lipid droplet abundance and modify myocellular distribution in adults with obesity.
Am J Physiol Endocrinol Metab. 2023 Nov 1;325(5):E466-E479. doi: 10.1152/ajpendo.00093.2023. Epub 2023 Sep 20.
Am J Physiol Endocrinol Metab. 2023.
PMID: 37729021
Metabolic dysfunction in obesity is related to impaired suppression of fatty acid release from adipose tissue by insulin.
Schleh MW, Ryan BJ, Ahn C, Ludzki AC, Varshney P, Gillen JB, Van Pelt DW, Pitchford LM, Howton SM, Rode T, Chenevert TL, Hummel SL, Burant CF, Horowitz JF.
Schleh MW, et al. Among authors: howton sm.
Obesity (Silver Spring). 2023 May;31(5):1347-1361. doi: 10.1002/oby.23734. Epub 2023 Mar 29.
Obesity (Silver Spring). 2023.
PMID: 36988872
Free PMC article.
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Exercise training remodels subcutaneous adipose tissue in adults with obesity even without weight loss.
Ahn C, Ryan BJ, Schleh MW, Varshney P, Ludzki AC, Gillen JB, Van Pelt DW, Pitchford LM, Howton SM, Rode T, Hummel SL, Burant CF, Little JP, Horowitz JF.
Ahn C, et al. Among authors: howton sm.
J Physiol. 2022 May;600(9):2127-2146. doi: 10.1113/JP282371. Epub 2022 Mar 20.
J Physiol. 2022.
PMID: 35249225
Free PMC article.
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Moderate-Intensity Exercise and High-Intensity Interval Training Affect Insulin Sensitivity Similarly in Obese Adults.
Ryan BJ, Schleh MW, Ahn C, Ludzki AC, Gillen JB, Varshney P, Van Pelt DW, Pitchford LM, Chenevert TL, Gioscia-Ryan RA, Howton SM, Rode T, Hummel SL, Burant CF, Little JP, Horowitz JF.
Ryan BJ, et al. Among authors: howton sm.
J Clin Endocrinol Metab. 2020 Aug 1;105(8):e2941-59. doi: 10.1210/clinem/dgaa345.
J Clin Endocrinol Metab. 2020.
PMID: 32492705
Free PMC article.
Clinical Trial.
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