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A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma.
Hoffmann RM, Crescioli S, Mele S, Sachouli E, Cheung A, Chui CK, Andriollo P, Jackson PJM, Lacy KE, Spicer JF, Thurston DE, Karagiannis SN. Hoffmann RM, et al. Among authors: thurston de. Cancers (Basel). 2020 Apr 22;12(4):1029. doi: 10.3390/cancers12041029. Cancers (Basel). 2020. PMID: 32331483 Free PMC article.
Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs).
Hoffmann RM, Mele S, Cheung A, Larcombe-Young D, Bucaite G, Sachouli E, Zlatareva I, Morad HOJ, Marlow R, McDonnell JM, Figini M, Lacy KE, Tutt AJN, Spicer JF, Thurston DE, Karagiannis SN, Crescioli S. Hoffmann RM, et al. Among authors: thurston de. Sci Rep. 2020 Jun 1;10(1):8869. doi: 10.1038/s41598-020-65860-x. Sci Rep. 2020. PMID: 32483228 Free PMC article.
125 results