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Mechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition.
Fogal V, Michopoulos F, Jarnuczak AF, Hamza GM, Harlfinger S, Davey P, Hulme H, Atkinson SJ, Gabrowski P, Cheung T, Grondine M, Hoover C, Rose J, Bray C, Foster AJ, Askin S, Majumder MM, Fitzpatrick P, Miele E, Macdonald R, Keun HC, Coen M. Fogal V, et al. Among authors: macdonald r. Arch Toxicol. 2024 May 17. doi: 10.1007/s00204-024-03771-w. Online ahead of print. Arch Toxicol. 2024. PMID: 38755480
Age-related dysregulation of the retinal transcriptome in African turquoise killifish.
Bergmans S, Noel NCL, Masin L, Harding EG, Krzywańska AM, De Schutter JD, Ayana R, Hu CK, Arckens L, Ruzycki PA, MacDonald RB, Clark BS, Moons L. Bergmans S, et al. Among authors: macdonald rb. Aging Cell. 2024 May 14:e14192. doi: 10.1111/acel.14192. Online ahead of print. Aging Cell. 2024. PMID: 38742929 Free article.
C9ORF72 deficiency results in neurodegeneration in the zebrafish retina.
Jaroszynska N, Salzinger A, Tsarouchas TM, Becker CG, Becker T, Lyons DA, MacDonald RB, Keatinge M. Jaroszynska N, et al. Among authors: macdonald rb. J Neurosci. 2024 Apr 24:e2128232024. doi: 10.1523/JNEUROSCI.2128-23.2024. Online ahead of print. J Neurosci. 2024. PMID: 38658168
Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Systematic Review and Network Meta-analysis for the American College of Physicians.
Drake T, Landsteiner A, Langsetmo L, MacDonald R, Anthony M, Kalinowski C, Ullman K, Billington CJ, Kaka A, Sultan S, Wilt TJ. Drake T, et al. Among authors: macdonald r. Ann Intern Med. 2024 May;177(5):618-632. doi: 10.7326/M23-1490. Epub 2024 Apr 19. Ann Intern Med. 2024. PMID: 38639549 Free article. Review.
Age-related dysregulation of the retinal transcriptome in African turquoise killifish.
Bergmans S, Noel NCL, Masin L, Harding EG, Krzywańska AM, De Schutter JD, Ayana R, Hu CK, Arckens L, Ruzycki PA, MacDonald RB, Clark BS, Moons L. Bergmans S, et al. Among authors: macdonald rb. bioRxiv [Preprint]. 2024 Mar 11:2024.02.21.581372. doi: 10.1101/2024.02.21.581372. bioRxiv. 2024. PMID: 38559206 Free PMC article. Updated. Preprint.
2,577 results